The present study investigated group and individual stability and predictors of somatic symptoms from childhood to adolescence in a population-based sample. 259 youth were evaluated at 6-12 years (M 8.1) and 8 years later (M 15.2). Sixteen somatic symptoms from the parent-rated Pediatric Behavior Scale were used for analyses, in addition to psychopathology subscales. Most somatic symptom prevalence rates decreased from childhood to adolescence. Group mean scores were relatively stable over time. Individual stability for the absence of somatic symptoms in childhood and adolescence was high, yet individual stability for the presence of somatic symptoms at both time points was low. Most symptoms remitted for the majority of youth. New cases in adolescence were common. Significant correlates of childhood and adolescent somatic symptoms varied. Longitudinal predictors were childhood somatic symptoms and adolescent medication status. Childhood psychopathology scores did not predict the total adolescent somatic symptom score.
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http://dx.doi.org/10.1007/s10578-024-01794-z | DOI Listing |
EClinicalMedicine
August 2024
Department of Psychosomatic Medicine and Psychotherapy, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Background: Despite the immense impact of Long COVID on public health and those affected, its aetiology remains poorly understood. Findings suggest that psychological factors such as depression contribute to symptom persistence alongside pathophysiological mechanisms, but knowledge of their relative importance is limited. This study aimed to synthesise the current evidence on psychological factors potentially associated with Long COVID and condition-relevant outcomes like quality of life.
View Article and Find Full Text PDFTobacco use is the leading cause of death globally and in the U.S. After decades of decline, driven by decreases in combusted tobacco use, nicotine product use has increased due to Electronic Nicotine Delivery Systems (ENDS), also known as e-cigarettes or vapes.
View Article and Find Full Text PDFHum Genome Var
January 2025
Division of Molecular Genetics, Center for Medical Science, Fujita Health University Hospital, Toyoake, Aichi, Japan.
UBA1 is an E1 ubiquitin-activating enzyme that initiates the ubiquitylation of target proteins and is thus a key component of the ubiquitin signaling pathway. Three disorders are associated with pathogenic variants of the UBA1 gene: vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome, lung cancer in never smokers (LCINS), and X-linked spinal muscular atrophy (XL-SMA, SMAX2). We here report a case of infantile respiratory distress syndrome followed by continuing neuromuscular symptoms.
View Article and Find Full Text PDFPLoS One
January 2025
Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Irritable Bowel Syndrome (IBS) patients and Somatization Symptom Disorder (SSD) patients experience somatization symptoms relative to their corresponding processes. IBS patients may also have a diagnosis of both IBS and SSD. Somatization symptoms cause significant psychological, emotional and social distress.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Rheumatology, University of Michigan Michigan Medicine, Ann Arbor, Michigan, USA
A man in his 60s suffered from refractory, biopsy-proven subacute cutaneous lupus erythematosus that required chronic, moderate dose steroids to manage. His rash was accompanied by arthralgias and negative autoantibody testing. His subacute lupus erythematosus (SCLE) was responsive to tofacitinib, but thrombotic complications limited the use of this medication.
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