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Occurrence of 'soft flesh' condition induced by Kudoa thyrsites parasite in the Iberian European sardine stock.
Parasitol Res
December 2024
Institute of Marine Research (IMR), Nordnesgaten 50, NO-5005, Bergen, Norway.
European sardine Sardina pilchardus is a commercially valuable coastal pelagic fish species. Spain is one of the largest sardine suppliers in Europe and the Iberian stock is of particular significance. Kudoa parasites are known to infect sardines causing the so-called 'soft flesh' condition; however, data on the occurrence of 'soft flesh' in this sardine stock are limited.
View Article and Find Full Text PDFRandom forest algorithm identifies miRNA signatures for breast cancer detection and classification from patient urine samples.
Ther Adv Med Oncol
December 2024
Clinic for Gynecology and Obstetrics, University Hospital RWTH Aachen, Aachen, Germany.
Background And Objectives: Breast cancer is the most common cancer in women, with one in eight women suffering from this disease in her lifetime. The implementation of centrally organized mammography screening for women between 50 and 69 years of age was a major step in the direction of early detection. However, the participation rate reaches approximately 50% of the eligible women, one reason being the painful compression of the breast, cited as a major issue for not participating in this very important program.
View Article and Find Full Text PDFFreshwater ecosystems face unprecedented challenges as the cumulative impact of human activities intensifies. While protected areas and species-specific conservation policies are widely implemented, their effectiveness remains difficult to gauge using traditional catch-based surveys. This research employed environmental DNA (eDNA) technology to assess the distribution of the endangered fish, , within the Yuanshui Unique Fish Species National Aquatic Germplasm Resources Reserve (YUFRR) in Hunan, China.
View Article and Find Full Text PDFDNA tensiometer reveals catch-bond detachment kinetics of kinesin-1, -2 and -3.
bioRxiv
December 2024
Department of Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania, USA.
Bidirectional cargo transport by kinesin and dynein is essential for cell viability and defects are linked to neurodegenerative diseases. The competition between motors is described as a tug-of-war, and computational modeling suggests that the load-dependent off-rate is the strongest determinant of which motor 'wins'. Optical tweezer experiments find that the load-dependent detachment sensitivity of transport kinesins is kinesin-3 > kinesin-2 > kinesin-1.
View Article and Find Full Text PDFReadiness assessment for cervical cancer elimination and prevention of human papillomavirus (HPV)-related cancers in Europe - are we winning the RACE?
Expert Rev Vaccines
December 2025
Public Policy Mid-European Region, MSD, Copenhagen, Denmark.
Introduction: To address the cervical cancer burden globally, the World Health Organization and European Union released strategies to facilitate HPV-related cancers prevention, including cervical cancer elimination. This research assessed European country level readiness to achieve cervical cancer elimination by adhering to such strategies.
Areas Covered: Readiness for cervical cancer elimination was assessed across a range of guiding questions relevant to three defined key domains: vaccination, screening, and treatment, each with two sub-domains focusing on decision making and implementation efforts.
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