The neurological process of mirror generalization in memory, also known as mirror symmetrization, presents a real dilemma for typically developing 5- to 6-year-olds when learning to write characters (digits and letters). Should they write the digit 3 oriented to the left, that is correctly, or to the right, which leads to its mirror image ε? It has been anecdotally suggested that boys are more prone to mirror-writing than girls, but there is no scientific evidence for this idea. The present article gathers data from 691 children in the upper section of the French école maternelle (age between 5 and 6 ½), who each wrote the digits 0 to 9 four times under dictation and not necessarily in their natural order. Both simple and complex (mixed-effects linear regression) statistical comparisons on the percentages of digit reversal, show a substantial difference: girls produce more mirror reversals than boys. And yet the reversal curves as a function of the digits are quite similar between the two sexes (r = .97). It has been proposed that mirror reversal of characters results from the left orientation of some of them (e.g., 3, 7, J, Z), that is, in an orientation contrary to the direction of writing in our Western cultures. The present investigation shows that (1) this character orientation hypothesis (choosing to write characters in the same orientation as sentence writing) better explains reversals than the counterclockwise hypothesis (children are trained to draw circles counter-clockwise to prepare for attached cursive writing); (2) the study of the stability of reversals additionally supports the explanation of mirror writing by the left orientation of the digits (1, 2, 3, 7 and, less obviously, 9); but (3) neither of the preceding findings (left-right orientation and stability) provided a convincing explanation for the aforementioned gender difference.
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http://dx.doi.org/10.1016/j.cortex.2024.10.014 | DOI Listing |
Exp Brain Res
December 2024
Division of Basic Biomedical Sciences, Laboratory of Neurological Sciences, The University of South Dakota, Sanford School of Medicine, Vermillion, SD, USA.
Injury to one cerebral hemisphere can result in paresis of the contralesional hand and subsequent preference of the ipsilesional hand in daily activities. However, forced use therapy in humans can improve function of the contralesional paretic hand and increase its use in daily activities, although the ipsilesional hand may remain preferred for fine motor activities. Studies in monkeys have shown that minimal forced use of the contralesional hand, which was the preferred hand prior to brain injury, can produce remarkable recovery of function.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland.
The study of the cortical basis of reading has greatly benefited from the use of naturalistic paradigms that permit eye movements. However, due to the short stimulus lengths used in most naturalistic reading studies, it remains unclear how reading of texts comprising more than isolated sentences modulates cortical processing. To address this question, we used magnetoencephalography to study the spatiospectral distribution of oscillatory activity during naturalistic reading of multi-page texts.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
December 2024
From the Department of Radiology, (Luca Pasquini), Yale New Haven Hospital, Yale Medical School, New Haven, CT, USA; Department of Radiology (Luca Pasquini, Mehrnaz Jenabi, Andrei I. Holodny), Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medical Physics (Antonio Napolitano, Leonardo Spitoni), Bambino Gesù Children's Hospital, Rome, Italy; Department of Engineering (Maurizio Schmid), University Roma Tre, Rome, Italy; Department of Radiology (Francesco Dellepiane) Bambino Gesù Children's Hospital, Rome, Italy; Department of Medical Physics (Kyung K. Peck), Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology (Andrei I. Holodny), Weill Medical College of Cornell University, New York, NY, USA; Department of Neuroscience (Andrei I. Holodny), Weill Cornell Graduate School of the Medical Sciences, New York, NY, USA.
Background And Purpose: The interaction between language and other cognitive networks in patients harboring brain tumors is poorly understood. We studied the modification of the cognitive control network (CCN) induced by brain tumors and its participation in language reorganization. We hypothesized that patients with brain tumors and reorganized language would show modification of the CCN compared to patients who remain left dominant.
View Article and Find Full Text PDFObjective: Functional MRI (fMRI) helps with the identification of eloquent cortex to assist with function preservation in patients who undergo epilepsy surgery. Language and memory tasks can even be used effectively in clinically involved pediatric patients. Most pediatric studies report on English speaking-only cohorts from English-dominant countries, yet languages other than English (LOEs) are increasingly prevalent in countries such as the US.
View Article and Find Full Text PDFEur J Investig Health Psychol Educ
December 2024
Department of Neurology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
The growing number of stroke survivors face physical, cognitive, and psychosocial impairments, making stroke a significant contributor to global disability. Various factors have been identified as key predictors of post-stroke outcomes. The aim of this study was to develop a standardized predictive model that integrates various demographic and clinical factors to better predict post-stroke cognitive recovery and depression in patients with ischemic stroke (IS).
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