Effect of agreement between clinician-rated and patient-reported PTSD symptoms on intensive outpatient treatment outcomes.

The level of agreement between self-reported posttraumatic stress disorder (PTSD) symptom severity, measured with the PTSD Checklist for DSM-5 (PCL-5), and severity measured via a clinician-rated measure, the Clinician Administered PTSD Scale for DSM-5 (CAPS-5), was tested as a predictor of the degree of improvement following a 2-week Intensive Outpatient Treatment Program (IOP). Differences in PTSD severity scores (PCL-5 minus CAPS-5) of US Veterans and service members with PTSD (N = 483) at Intake were used to categorize patients into 3 agreement groups: Congruent reporters, Limited Over-reporters and Extensive Over-reporters. A linear mixed model tested whether agreement group impacted the degree of improvement, measured as reduction in PCL-5 score, from IOP baseline to completion. The mean difference between the PCL-5 and CAPS-5 scores was 17.5 ± 13.1 points. Mean modeled reduction in PCL-5 scores from IOP Baseline to IOP Completion for Limited Over-reporters was -21.3 points (95 %CI -23.6, -19.1), which was significantly less than the reduction for Extensive Over-reporters (-27.6, 95 %CI -32.1, -23.1, p<.001), but not significantly different from Congruent reporters (-18.0, 95 %CI -22.7, -13.3, p=.17). Patients who most over-report their PTSD symptoms compared to trained clinicians show steepest declines in PTSD symptom severity with treatment. Personalizing treatment for PTSD may benefit from understanding the mechanisms contributing to these differences.