Introduction: Physical inactivity is a major global public health concern, increasing the risk factor of non-communicable diseases (NCDs) and mortality. The WHO has initiated the Global Action Plan on Physical Activity to reduce global physical inactivity by 15% by 2030. Rapid urbanisation and insufficient physical activity in the Global South have significant implications for public health, leading to increased NCDs. Understanding physical inactivity and related risk factors among adults is essential in addressing the growing NCD epidemic. This study aims to estimate the pooled prevalence of physical inactivity and its associated risk factors among adults in Eastern African countries.
Methods And Analysis: This review protocol will follow the Preferred Reporting Items for Systematic Review and Meta-Analysis (2020) Guideline. A comprehensive search will be conducted using the CoCoPop (condition, context, population) frameworks to include all observational studies published from 1 January 2010 to 31 October 2024. Databases such as PubMed, Scopus, Embase, CINAHAL, Web of Science, Science Direct and Google Scholar will be searched. Studies with citations without an abstract or full text and qualitative studies will be excluded. The Joanna Briggs Institute critical appraisal tool will be used to assess the quality of each study. The heterogeneity of studies will be quantified using the I statistic, and a fixed-effects or random-effects model will be used for the pooled analysis. Publication bias will be assessed using visual (funnel plot) and statistical methods. The study countries will be the basis for subgroup analysis, and sensitivity analysis will be used to see how one study's results may affect the estimate as a whole.
Ethics And Dissemination: Ethical approval is not required for this systematic review. The results will be disseminated through peer-reviewed publications and conference presentations. Furthermore, this systematic review and meta-analysis will be used to generate comprehensive and robust evidence for public health interventions.
Prospero Registration Number: CRD42024567592.
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http://dx.doi.org/10.1136/bmjopen-2024-084073 | DOI Listing |
BMJ Open
January 2025
Northwell Health, New Hyde Park, New York, USA.
Introduction: Cardiovascular disease (CVD) is the leading cause of mortality worldwide, though it may be prevented by increasing physical activity (PA). When behaviour change techniques (BCTs) are bundled together, they increase PA, though which individual BCTs increase PA (and the behavioural mechanism of action (MoA) responsible for said increase) have not been studied. The aim of this study is to conduct a randomised factorial experiment to determine which of four BCTs significantly engage the proposed MoA-self-efficacy for PA-in adults at risk for CVD.
View Article and Find Full Text PDFAm J Health Promot
January 2025
Department of Health Management and Policy, College for Public Health and Social Justice, Saint Louis University, St. Louis, MO, USA.
Purpose: Examining the associations between sleep duration and lifestyle risk factors and assessed whether sex modify such associations among U.S. adolescents.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
The Jackson Laboratory, Bar Harbor, ME, USA.
Background: Late-onset Alzheimer's disease (LOAD) is the leading cause of dementia and a major contributor to increased mortality. Recent human datasets have revealed many LOAD genetic risk factors that are correlated with the degree of AD burden. Further, the complexity and heterogeneity of LOAD appears to be promoted by interactions between genetics and environmental factors such as diet, sedentary behavior, and exposure to toxicants, like lead (Pb), cadmium (Cd), and arsenic (As).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Biobank for Aging Studies of the University of São Paulo, São Paulo, Brazil.
Background: Previous studies suggest an association between Alzheimer's disease and carotid artery atherosclerosis. However, the association between atherosclerotic carotid plaque composition and Alzheimer's disease pathology (neuritic plaques and neurofibrillary tangles) has not been explored yet.
Method: Carotid arteries were dissected and the segments with the largest obstruction in the carotid bifurcation, and the common and internal carotid arteries were obtained.
Alzheimers Dement
December 2024
Centre for Brain Research, Indian Institute of Science, Bangalore, Karnataka, India.
Background: Evidence from multiple converging sources has demonstrated the clear benefits of physical activity in promoting mental health and improving cognitive function. However, more than 54% of Indians do not engage in the recommended amount of physical activity. The present study aims to explore the association of physical activity with cognitive abilities among the elderly aging population in an urban Indian setting.
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