Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/svn-2024-003868 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Semaglutide protects against diabetes-associated cardiac inflammation via Sirt3-dependent RKIP pathway.
Br J Pharmacol
December 2024
Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Background And Purpose: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) exert cardiovascular benefits in diabetic patients, but the underlying mechanisms remain incompletely understood. Semaglutide, a novel long-acting GLP-1RA, has shown a reduced risk of cardiovascular events. Based on these results, we investigated the therapeutic potential of semaglutide in diabetic cardiomyopathy and sought to elucidate the underlying mechanisms.
View Article and Find Full Text PDFGenetic parameters and correlations between growth traits and packed cell volume of N'Dama cattle in the Gambia.
Trop Anim Health Prod
December 2024
Animal Breeding and Genomic Group, Department of Animal Science, University Egerton, PO Box 536-20115, Egerton, Kenya.
The evolution of body weight under the natural trypanosome challenge and its association with disease tolerance to trypanosomosis is of utmost economic importance in cattle. This study estimated heritability for growth traits and packed cell volume (PCV) and their genetic correlations in the N'Dama cattle in the Gambia. A total of 2,488, 2,442, 1,471, 1,934, and 1,452 bodyweight records at 12 months (WT12), 16 months (WT16), 18 months (WT18), 24 months (WT24), 36 months (WT36) and 50 months (WT50) and 1,782, 1,800, 1,844, 1,608, and 1,459 records for PCV at 12 months (PCV12) 18 months (PCV18), 24 months (PCV24), 36 months (PCV36), and 50 months (PCV50), respectively, were analysed.
View Article and Find Full Text PDFRegional Hereditary Cancer Program in Chile: A scalable model of genetic counseling and molecular diagnosis to improve clinical outcomes for patients with hereditary cancer across Latin America.
Biol Res
December 2024
Unidad de Innovación en Prevención y Oncología de Precisión Centro Oncológico, Facultad de Medicina, Unidad de Innovación en Prevención y Oncología de Precisión Universidad Católica del Maule, Talca, 3480094, Chile.
Background: Breast cancer is a leading cause of cancer-related mortality worldwide, with hereditary forms accounting for approximately 10% of cases. In Chile, significant gaps exist in genetic counseling and testing, particularly within the public health system. This study presents the implementation and outcomes of the first regional hereditary cancer program in the Maule region of Chile, aimed at improving detection and management of hereditary breast cancer.
View Article and Find Full Text PDFDo children with a Noonan syndrome-like RASopathy and avoidant/restrictive food intake disorder benefit from behavioral therapy?
Eur J Pediatr
December 2024
Dept. of Research and Development, SeysCentra, Malden, The Netherlands.
Unlabelled: Children with Noonan syndrome-like RASopathies are at increased risk for developing feeding problems due to comorbid organic impairments at an early age, such as gastrointestinal problems or other organicity. Their feeding problems can ultimately often be classified as avoidant/restrictive food intake disorder, for which behavioral therapy is the first-choice treatment. The research question in this study is whether this treatment leads to similar results as in children without these RASopathies.
View Article and Find Full Text PDFA detailed inquiry of the differences between headphones and loudspeakers influences on dynamic postural task performance.
Exp Brain Res
December 2024
Music and Audio Research Laboratory, New York University, New York, USA.
We examined the impact of auditory stimuli and their methods on a dynamic balance task performance. Twenty-four young adults wore an HTC Vive headset and dodged a virtual ball to the right or left based on its color (blue to the left, red to the right, and vice versa). We manipulated the environment by introducing congruent (auditory stimuli from the correct direction) or incongruent (auditory stimuli played randomly from either side) and comparing a multimodal (visual and congruent auditory stimuli) to unimodal (visual or auditory stimuli) presentation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!