Botulinum Toxin and Electrophysiological Intervention Improve Post-Surgical Breast Entdoprosthetics: A Clinical Trial Study.

Introduction: The majority of plastic surgeon specialists note a distinct tendency to increase the number of breasts endoprosthetic surgeries with silicone implants in the Republic of Uzbekistan - the number of such surgeries now reaches 3-4 thousand annually. Breast replacement for aesthetic purposes is widespread throughout the world and has been rapidly spreading in Uzbekistan in recent years. Due to surgical endoprosthetics of mammary gland tissue with silicone implants, both in the early and late postoperative periods, quite often the patient's body experiences typical postoperative pain, which, if subclinical, requires constant dynamic monitoring and preventive rehabilitation procedures. Rehabilitation measures are a prerequisite for a successfully performed aesthetic surgery to enlarge the mammary glands.

Materials And Methods: To address the effectiveness of intramuscular botulinum toxin A and the INDIBA electromagnetic field electrophysiology we used, a prospective randomized trial was designed to evaluate the effectiveness of patient-reported postoperative pain and pain reduction in these settings.

Results: The results of the conducted research allow us to conclude that the course of electrophysiological influence by INDIBA preparation, conducted in the first week, daily, i.e. 7 procedures after aesthetic breast endoprosthetics, significantly increases the efficiency of anesthetic effect of botulinum toxin type A drug administration 14 days before the intervention.

Discussion:  These studies results allow us to conclude that a course of electrophysiological treatment with INDIBA, conducted in the first week after aesthetic breast endoprosthetics, significantly increases the effectiveness of the analgesic effect of botulinum toxin.

Conclusion: Thus, the given results are convincing in terms of the fact that the proposed complex of rehabilitation measures after aesthetic endoprosthetics of mammary glands in the form of parenteral intramuscular administration of botulinum toxin preparation and a course of electrophysiological influence by electromagnetic field has a statistically significant pathogenetically-based pronounced and prolonged analgesic effect in the postoperative period.