This is the first case report of a vitamin E-blended polyethylene liner fracture after total hip arthroplasty. Our case highlights the importance of considering a vitamin E-blended polyethylene liner fracture, the interposition of fracture fragments between the articulating surfaces after dislocation and blocked successful reduction.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602437PMC
http://dx.doi.org/10.1002/ccr3.9561DOI Listing

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This is the first case report of a vitamin E-blended polyethylene liner fracture after total hip arthroplasty. Our case highlights the importance of considering a vitamin E-blended polyethylene liner fracture, the interposition of fracture fragments between the articulating surfaces after dislocation and blocked successful reduction.

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Introduction: Bone preservation and long-term survival are the main challenges in cementless total hip arthroplasty (THA). A good bone stock is especially important for adequate anchorage of the cup in revision cases. However, the optimal acetabular cup design for preserving good bone stock is still unclear.

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Cup positioning and its effect on polyethylene wear of vitamin E- and non-vitamin E-supplemented liners in total hip arthroplasty: radiographic outcome at 5-year follow-up.

Arch Orthop Trauma Surg

March 2023

Department of Orthopedics, Trauma and Reconstructive Surgery, Marienhospital Mülheim an Der Ruhr, Chair of Orthopedics and Trauma Surgery, University of Duisburg-Essen, Essen, Germany.

Background: Aseptic loosening remains a challenging problem after total hip arthroplasty. Accurate cup placement and supplementation of antioxidants in acetabular liners might reduce material failure rates. The aim of this study is to assess the effect of the cup position on the wear behaviour of UHMWPE-XE and UHMWPE-X liners in vivo using virtual radiographs.

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Determination of optimal concentration of vitamin E in polyethylene liners for producing minimal biological response to prosthetic wear debris.

J Biomed Mater Res B Appl Biomater

July 2022

Department of Orthopedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

The introduction of vitamin E-blended ultra-high molecular weight polyethylene (VE-UHMWPE) for use in prosthetic components of hip implants has resulted in the production of implants that have excellent mechanical properties and substantially less adverse cellular responses. Given the importance of a biological response to wear in the survival of a prosthesis, we generated wear debris from UHMWPE that had been prepared with different concentrations of vitamin E of 0.1, 0.

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Purpose: This study aims to identify differentially expressed genes (DEGs) in macrophages exposed to ultra-high-molecular-weight polyethylene (UHMWPE) or vitamin E-blended UHMWPE (VE-UHMWPE) particles, thereby providing potential targets for the treatment of inflammatory osteolysis.

Methods: The GSE104589 dataset of genome expression in macrophages exposed to UHMWPE and VE-UHMWPE was downloaded from the Gene Expression Omnibus database to identify DEGs. Functional enrichment analysis was performed using DAVID, and the corresponding protein-protein interaction (PPI) network was constructed from the STRING database.

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