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Comment on "Dense Tumor-Infiltrating Lymphocytes (TILs) in Liver Metastasis From Colorectal Cancer Are Related to Improved Overall Survival".
J Surg Oncol
November 2024
Department of Anorectal Surgery, Ningbo No.2 Hospital, Ningbo, Zhejiang, China.
Creating a path during melanoma amoeboid migration: When too crowded, start worrying.
Dev Cell
September 2024
Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, 28029 Madrid, Spain; Instituto de Investigación Sanitaria Hospital Universitario La Paz (IdiPAZ), 28046 Madrid, Spain. Electronic address:
Invasion of some cancer cells into surrounding tissues requires traversing dense environments, although the precise mechanisms are unclear. In this issue of Developmental Cell, Driscoll et al. (2024) show that amoeboid melanoma cells create tunnels via bleb-driven abrasion of the extracellular matrix (ECM) without proteolytic degradation, a mechanism coined "worrying.
View Article and Find Full Text PDFBreast Cancer Screening Using Mammography, Digital Breast Tomosynthesis, and Magnetic Resonance Imaging by Breast Density.
JAMA Intern Med
October 2024
The Dartmouth Institute for Health Policy and Clinical Practice, Departments of Medicine and of Community and Family Medicine, and Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.
Importance: Information on long-term benefits and harms of screening with digital breast tomosynthesis (DBT) with or without supplemental breast magnetic resonance imaging (MRI) is needed for clinical and policy discussions, particularly for patients with dense breasts.
Objective: To project long-term population-based outcomes for breast cancer mammography screening strategies (DBT or digital mammography) with or without supplemental MRI by breast density.
Design, Setting, And Participants: Collaborative modeling using 3 Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer simulation models informed by US Breast Cancer Surveillance Consortium data.
Editorial Comment on "Efficacy and safety of dose-dense gemcitabine plus cisplatin as neoadjuvant chemotherapy for muscle-invasive bladder cancer".
Int J Urol
October 2024
Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.
Editorial Comment to "Efficacy and safety of dose-dense gemcitabine plus cisplatin as neoadjuvant chemotherapy for muscle-invasive bladder cancer".
Int J Urol
October 2024
Department of Urology, St. Marianna University School of Medicine, Kawasaki City, Kanagawa, Japan.
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