Imprinting of the paternal marsupial X chromosome by DNA methylation.

Trends Genet

Department of Environment and Genetics, La Trobe University, Melbourne, VIC 3168, Australia. Electronic address:

Published: January 2025

Why is it that the X chromosome that comes from the male parent is inactivated in female marsupials, female mice, and even female mealy bugs, or the whole paternal chromosome complement in some weird flies? A new paper by Milton et al. now reveals DNA methylation patterns established in the male germline before meiosis in wallabies that may constitute the elusive paternal imprint.

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Source
http://dx.doi.org/10.1016/j.tig.2024.10.011DOI Listing

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