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Implementing a Responsible Conduct of Research Curriculum for an Undergraduate Summer Clinical Research Program in Quantitative Sciences.
J Med Educ Curric Dev
January 2025
Department of Health Policy and Management, Columbia University Mailman School of Public Health, New York, NY, USA.
Objectives: Instilling the principles of ethical and responsible medical research is critical for educating the next generation of clinical researchers. We developed a responsible conduct of research (RCR) workshop and associated curriculum for undergraduate trainees in a quantitative clinical research program.
Methods: Topics in this 7-module RCR workshop are relevant to undergraduate trainees in quantitative fields, many of whom are learning about these concepts for the first time.
Pareto in Prison.
Behav Sci Law
January 2025
School of Criminal Justice and Criminology, Texas State University, San Marcos, Texas, USA.
The Pareto principle is based on the concept that roughly 80% of outcomes are generated by 20% of inputs, efforts, or contributors within a group. Using a national sample of U.S.
View Article and Find Full Text PDFEmpowering Privacy Through Peer-Supervised Self-Sovereign Identity: Integrating Zero-Knowledge Proofs, Blockchain Oversight, and Peer Review Mechanism.
Sensors (Basel)
December 2024
School of Cyberspace, Hangzhou Dianzi University, Hangzhou 310005, China.
Frequent user data breaches and misuse incidents highlight the flaws in current identity management systems. This study proposes a blockchain-based, peer-supervised self-sovereign identity (SSI) generation and privacy protection technology. Our approach creates unique digital identities on the blockchain, enabling secure cross-domain recognition and data sharing and satisfying the essential users' requirements for SSI.
View Article and Find Full Text PDFSynergistic effects of a sequential recirculation electrochemical system combined with low-cost UV-LEDs on the gram-negative bacteria inactivation.
Environ Sci Pollut Res Int
January 2025
Grupo de Investigación en Ciencias Biológicas y Químicas, Facultad de Ciencias, Universidad Antonio Nariño, Bogotá D.C, Colombia.
In this work, an electrochemical system combined with low-cost UV-LEDs was implemented for the inactivation of Escherichia coli and Pseudomonas aeruginosa. The individual elimination of these bacteria was followed by plate counting and flow cytometry, as complementary techniques to establish the cell inactivation and non-viability, respectively. The contribution of the different parts of the disinfection system (anode, cathode, and light) was determined.
View Article and Find Full Text PDFAssessing institutional responsibility in scientific misconduct: A case study of enoximone research by Joachim Boldt.
Clin Trials
December 2024
Institute of General Practice and Public Health, Claudiana-College of Health Professions, Bolzano, Italy.
Background: Enoximone, a phosphodiesterase III inhibitor, was approved in Germany in 1989 and initially proposed for heart failure and perioperative cardiac conditions. The research of Joachim Boldt and his supervisor Gunter Hempelmann came under scrutiny after investigations revealed systematic scientific misconduct leading to numerous retractions. Therefore, early enoximone studies by Boldt and Hempelmann from 1988 to 1991 were reviewed.
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