In this study, we have characterized and sequenced the whole genome of a new member of the Kuttervirus genus, Salmonella phage vB_Sen_ST2. This phage selectively targets Salmonella enterica serovars Typhi and Typhimurium, which are major etiologic agents of salmonellosis worldwide. Its genome consists of a linear, double-stranded DNA of 156,028 bp, with a G + C content of 44.93 %. Based on our results, Salmonella phage vB_Sen_ST2 presents suitable features to be considered as a potential control agent against Salmonella enterica serovars that are responsible for salmonellosis.
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http://dx.doi.org/10.1016/j.micpath.2024.107178 | DOI Listing |
Front Cell Infect Microbiol
December 2024
College of Agriculture and Biology, Liaocheng University, Liaocheng, Shandong, China.
Abortusequi ( Abortusequi) is the primary cause of abortions in equine animals, and can cause serious foodborne illness. Thus, effective biocontrol strategies are needed to decontaminate and control the emergence of foodborne diseases. In recent years, phages have been used as a new strategy for modulating foodborne pathogens and food safety.
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December 2024
Department of Agricultural Sciences, University of Naples Federico II, Portici, Italy.
serovar Rissen ( Rissen) is an emerging causative agent of foodborne diseases. The current emergence of antibiotic resistance makes necessary alternative therapeutic strategies. In this study, we investigated the potential of a phage-resistant strain of Rissen (R) as a tool for developing an effective lipopolysaccharide (LPS)-based vaccine.
View Article and Find Full Text PDFFront Microbiol
December 2024
Department of Food Science and Technology, The Ohio State University, Columbus, OH, United States.
Advances in bacteriophage genome sequencing and regulatory approvals of some bacteriophages in various applications have renewed interest in these antibacterial viruses as a potential solution to persistent food safety challenges. Here, we analyzed in depth the genome of the previously studied bacteriophage OSYSP (phage OSYSP), revealed its application-related characteristics, and optimized its enumeration techniques for facilitating industrial implementation. We previously sequenced phage OSYSP genome completely by combining results from Illumina Miseq and Ion Torrent sequencing platforms and completing the remaining sequence gaps using PCR.
View Article and Find Full Text PDFBioinform Biol Insights
December 2024
Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in is still under investigation. This study explores the distribution and impact of CRISPR-Cas systems on antibiotic resistance by analyzing 316 genomes.
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December 2024
Experimental Zooprophylactic Institute of Abruzzo and Molise "G. Caporale", Teramo, Italy.
Introduction: spp. is the second most common bacteria associated with foodborne gastrointestinal outbreaks in humans, with the highest contamination levels in meat, especially poultry. subsp.
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