The current study aims to identify research hotspots and trends in Monkeypox (MPX). A total of 2655 MPX-related articles published from 1961 to 2023 were extracted from the Scopus database. Data were analyzed using Scopus Analytics, Microsoft Excel, Bibliometrix, and VOSviewer. The number of MPX papers has been increasing annually, particularly since the most recent outbreak. The United States and India have been productive in this area. The most cited and productive scholar in the field is Inger K. Damon. The MPX research theme map shows clusters with various centralities and densities, focusing on deep learning, molecular docking, and orthopoxviruses. Over the last decade, key terms include "transmission," "pandemic," "deep learning," "docking," "Democratic Republic of Congo," "Ebola," "virulence," "modified vaccinia Ankara," and "orthopoxvirus." Researchers can utilize existing findings to steer future research on this illness, prepare for potential pandemics, and address bioterrorist threats.
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Monkeypox virus infection in pregnancy: description of two cases reported to the Colombian National Institute of Health.
APMIS
January 2025
Clínica del Country, Gynecology and Obstetrics Service, Bogotá D.C, Colombia.
Monkeypox (mpox), caused by the MPOXV (monkeypox virus), has been endemic in Africa since its first identification in 1958. However, in May 2022, the world witnessed the first global outbreak associated with the West African clade. Even though thousands of cases have been recorded, our understanding of vertical transmission during pregnancy remains restricted due to an absence of reported cases in pregnant women and a lack of adequate clinical descriptions.
View Article and Find Full Text PDFThe perspectives and knowledge of patients with cancer on mpox and mpox vaccination: a cross-sectional study.
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Department of Medical Oncology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Objective: The recent outbreak of monkeypox (mpox) poses significant public health challenges, particularly for immunocompromised populations such as patients with cancer. However, misinformation poses a significant challenge during new outbreaks for patients with chronic diseases, as observed during the COVID-19 pandemic. Therefore, we aimed to assess perspectives and knowledge of patients with cancer on mpox and their willingness to receive mpox vaccination.
View Article and Find Full Text PDFEvolutionary variation of the monkeypox virus detected for the first time in Nantong, Jiangsu.
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Key Laboratory of Medicine, Nantong Center for Disease Control and Prevention, 189 GongnongnanRoad, Chongchuan District, Nantong, 226007, China.
Monkeypox (MPOX) is a zoonotic disease caused by Orthopoxvirus monkeypox (MPXV), belonging to the Orthopoxvirus genus, and exhibits symptoms similar to smallpox. In 2024, the monkeypox outbreak in the Democratic Republic of the Congo continued to develop, raising widespread global public health concerns. In September 2023, the first local monkeypox outbreak was reported in Nantong, Jiangsu Province, China.
View Article and Find Full Text PDFEffectiveness of Tecovirimat in Mpox Cases: A Systematic Review of Current Evidence.
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SR Sanjeevani Hospital, Kalyanpur, Siraha, Nepal.
Mpox, formerly known as monkeypox, has re-emerged as a significant global health concern, particularly during the widespread outbreak of 2022. As an orthopoxvirus related to the eradicated smallpox virus, mpox has been primarily managed with smallpox vaccines and treatments, including the antiviral agent Tecovirimat. This systematic review aims to evaluate the effectiveness and safety of Tecovirimat in treating mpox, focusing on its use during the 2022 outbreak, especially among high-risk populations, including men who have sex with men and people living with HIV.
View Article and Find Full Text PDFCDCM: a correlation-dependent connectivity map approach to rapidly screen drugs during outbreaks of infectious diseases.
Brief Bioinform
November 2024
School of Mathematics and Statistics, HNP-LAMA, Central South University, Changsha 410083, Hunan, China.
In the context of the global damage caused by coronavirus disease 2019 (COVID-19) and the emergence of the monkeypox virus (MPXV) outbreak as a public health emergency of international concern, research into methods that can rapidly test potential therapeutics during an outbreak of a new infectious disease is urgently needed. Computational drug discovery is an effective way to solve such problems. The existence of various large open databases has mitigated the time and resource consumption of traditional drug development and improved the speed of drug discovery.
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