AI Article Synopsis
- This study examines the risk factors for Alzheimer disease patients who also experience neuropsychiatric symptoms (ADNPS) in both males and females.
- Researchers analyzed data from a regional Alzheimer care center using univariate analysis and logistic regression to identify these risk factors.
- Findings indicate that male ADNPS patients are linked to dyslipidemia and cerebral infarction, while female ADNPS patients have a stronger association with chronic heart failure.
Article Abstract
Background: This study investigates risk factors in the population of Alzheimer disease (AD) patients with NPS (ADNPS).
Method: Baseline risk factors associated with male and female ADNPS were examined using data from a regional AD care center. Univariate analysis was used to determine factors in male and female patients, while logistic regression models were developed to generate odds ratios (OR) to predict risk factors that are associated with male or female ADNPS.
Results: In the adjusted analysis, dyslipidemia (OR = 0.630, 95 % CI, 0.431-0.992, P = 0.017), thyroid dysfunction (OR = 0.549, 95 % CI, 0.377-0.798, P = 0.002), and cerebral infarction (OR = 0.684, 95 % CI, 0.472-0.991, P = 0.0085) were associated with male ADNPS patients, whereas chronic heart failure (OR = 1.408, 95 % CI, 0.953-2.079, P = 0.0085) was associated with female ADNPS patients.
Conclusions: Our results reveal that female ADNPS patients were associated with heart failure, whereas male patients were associated with dyslipidemia and cerebral infarction.
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| http://dx.doi.org/10.1016/j.gerinurse.2024.11.001 | DOI Listing |
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