The present study aimed to compare peak oxygen uptake (V̇Opeak), peak heart rate (HRpeak), and peak Opulse during an incremental and a verification test performed on the same day in hand-cyclists with spinal cord injury (SCI). Eight competitive SCI hand-cyclists (age: 23 ± 2.7 years; V̇Opeak: 36.3 ± 14.0 mL.kg.min) performed a maximal incremental handcycling test and a verification test to exhaustion at 100% of the peak speed on an oversized treadmill. The V̇Opeak, HRpeak, and peak Opulse (i.e., VO/HR) were compared between incremental and verification tests. Absolute and relative V̇Opeak obtained in the verification test (2.51 ± 0.96 L.min; 36.3 ± 14.0 mL.kg.min) were significantly higher than values obtained in the incremental test (2.24 ± 0.79 L.min; 33.5 ± 12.9 mL.kg.min; < 0.05). The mean differences (95% CL) of absolute and relative V̇Opeak between tests were 8.2% (3.3%-13.2%) and 10.9% (4.3%-18.1%), respectively. There was no difference in HR peak (incremental: 169 ± 24 bpm; verification 167 ± 25 bpm; = 0.130). Peak Opulse from the verification test (14.6 ± 4.7 mL.beat) was higher than incremental test (13.0 ± 3.8 mL.beat; = 0.007). In conclusion, the verification test elicited greater V̇Opeak and Opulse than a two-phase incremental test despite the similar HRpeak. This indicates that for this progressive protocol lasting ≥25 min, the verification phase adds value to determining V̇Opeak in SCI athletes.
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http://dx.doi.org/10.1139/apnm-2024-0193 | DOI Listing |
Virol J
January 2025
Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, Guangdong, 518118, China.
Background: SHEN26 (ATV014) is an oral RNA-dependent RNA polymerase (RdRp) inhibitor with potential anti-SARS-CoV-2 activity. Safety, tolerability, and pharmacokinetic characteristics were verified in a Phase I study. This phase II study aimed to verify the efficacy and safety of SHEN26 in COVID-19 patients.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Department of Dairy and Process Engineering, Food Sciences and Nutrition, Poznan University of Life Sciences, Wojska Polskiego 31, 60-624 Poznan, Poland.
The strength and energy of processed biological materials depend, among others, on their properties. Despite the numerous studies available, the relationship between the internal structure of corn grains and their mechanical properties has not yet been explained. Hence, the aim of the work is to explore the relationship between the internal composition of maize kernels and its mechanical properties by studying the impact of the maize seed coat thickness on its breakage susceptibility.
View Article and Find Full Text PDFSports Med
January 2025
School of Athletic Performance, Shanghai University of Sport, No. 200, Henren Road, Shanghai, 200438, China.
Background: Post-activation performance enhancement (PAPE) has demonstrated efficacy in acutely improving athletic performance. However, its distinction from general warm-up (GW) effects remains ambiguous, and experimental designs adopted in most PAPE studies exhibit important limitations.
Objectives: The aims of this work are to (i) examine the effects of research methodology on PAPE outcomes, (ii) explore PAPE outcomes in relation to comparison methods, performance measures, GW comprehensiveness, recovery duration, participants' characteristics, conditioning activity (CA) parameters, and (iii) make recommendations for future PAPE experimental designs on the basis of the results of the meta-analysis.
Cells
January 2025
Department of Functional and Evolutionary Ecology, University of Vienna, Djerassiplatz 1, A-1030 Vienna, Austria.
Contaminations are challenging for monocultures, as they impact the culture conditions and thus influence the growth of the target organism and the overall biomass composition. In phycology, axenic cultures comprising a single living species are commonly strived for both basic research and industrial applications, because contaminants reduce significance for analytic purposes and interfere with the safety and quality of commercial products. We aimed to establish axenic cultures of , known as the food additive "Spirulina".
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Objectives: To determine the mortality-related risk factors for carbapenem-resistant Enterobacteriaceae (CRE) infection in hospitalized patients and to compare the clinical efficacy of different antimicrobial regimen.
Methods: Data were retrospectively collected from a 3,500-bed regional medical center between January 2021 and June 2022. Mortality-related risk factors were analyzed by the Cox proportional regression model for multivariate analysis.
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