AI Article Synopsis
- The study investigates kidney problems caused by chronic filariasis, a significant health issue in eastern and north-eastern India.
- It analyzes biopsy data from eight patients with chronic filariasis who experienced symptoms like nephrotic syndrome and renal failure over a mean duration of about 16 years.
- The findings highlight various kidney disease patterns and emphasize the necessity for further research on the renal implications of filariasis in affected regions.
Article Abstract
The study presents renal manifestations in chronic filariasis, a substantial health concern in the eastern and north-eastern regions of India. The study is a retrospective analysis of a renal biopsy series of patients with chronic filariasis from a tertiary care hospital in Odisha. It involves eight cases of chronic filariasis. Common indications of biopsy were nephrotic syndrome, chyluria, and unexplained renal failure. The mean duration from the diagnosis of filariasis to the onset of glomerular diseases was 15.75 years, SD ± 4.2 years. Patients were followed up for a minimum of 6 months. Renal histopathology revealed various patterns, including membranous nephropathy, minimal change disease, IGA nephropathy, and membranoproliferative glomerulonephritis. The study fills a critical gap in the literature by elucidating renal biopsy findings in chronic filariasis. The multifaceted nature of this disease underscores the need for continued research to understand kidney diseases due to filariasis, especially in endemic regions.
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| http://dx.doi.org/10.1089/vbz.2024.0038 | DOI Listing |
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Article Synopsis
- The study investigates kidney problems caused by chronic filariasis, a significant health issue in eastern and north-eastern India.
- It analyzes biopsy data from eight patients with chronic filariasis who experienced symptoms like nephrotic syndrome and renal failure over a mean duration of about 16 years.
- The findings highlight various kidney disease patterns and emphasize the necessity for further research on the renal implications of filariasis in affected regions.
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Front Pharmacol
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Unit of Molecular Epidemiology, ICMR-Vector Control Research Centre, Puducherry, India.
Background: The success of mass drug administration (MDA) for lymphatic filariasis (LF) elimination relies on achieving a participation rate of at least 65% within the endemic community. However, participation of sub-population in the community varies and a significant treatment gap among the elderly population, remains to be addressed. The present study explores the factors influencing the elderly participation in MDA and propose possible solutions to bridge the gap.
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