Background: Cervical fixation is a common treatment for conditions like vertebral fractures, osteosarcoma, osteomyelitis, arthritis, and congenital disorders. The study was designed to assess the occurrence of high-riding vertebral artery (HRVA), narrow C2 pedicles (NC2P) and ponticulus posticus (PP), which pose risks of injuring vertebral artery (VA) during screw placement in cervical fixation procedures.
Methods: The study examined the prevalence of HRVA, NC2P and PP in 382 pedicle sides of the C2 vertebra using computed tomographic angiography scans. Specific measurements were taken, including the internal height (C2InH), and isthmus height (C2IsH) of C2, as well as NC2P width.
Results: HRVA was identified by specific measurements: C2IsH of ≤ 5 mm and/or C2InHof ≤ 2 mm. NC2P was defined as NC2P width ≤ 4 mm. The reliability between observers and within the same observer, along with the consistency across different software, was assessed. At least one HRVA was found in 9.6% of patients and at least one NC2P in 13% of patients. Females demonstrated higher rates of HRVA and NC2Ps on the left side, with right-side figures at 10.5% and 11.7% for HRVA and NC2Ps respectively, and left side figures at 14.1% for both. Males exhibited a reserve pattern, with higher rates on the right side, marked by 10.3% HRVA and 15% NC2Ps, compared to 5.6% and 11.3% on the left. Furthermore, males showed a significantly higher occurrence of NC2Ps over HRVA on both sides. The presence of PP with NC2Ps detected in 44% of cases, and with HRVA in 16% of cases, a difference found to be statistically significant.
Conclusions: The digital models incorporating HRVA, NC2P, and PP facilitated a comprehensive analysis of the VA pattern, assessment of the virtual screw trajectory line for VA pedicles, and the designation of specific regions during the procedure, ensuring increased safety planning instrumentation.
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http://dx.doi.org/10.1007/s00276-024-03526-3 | DOI Listing |
Int J Mol Sci
December 2024
Sathyamoorthy Laboratory, Department of Medicine, Burnett School of Medicine at TCU, Fort Worth, TX 76104, USA.
After reporting the first known clinical case associating compound heterozygous single-nucleotide variants in Exon 2 of to aortic aneurysmal and iliac dissection, we began prospective surveillance in our vascular genetic practice for similar cases. Herein, we present nine (9) subjects from a total cohort of 135 with arterial aneurysms or dissections who revealed single-nucleotide variants in with no other alterations in a panel of 35 genes associated with aneurysmal and dissection disorders. Five out of nine (5/9) single-nucleotide variants were in Exon 1, and four out of nine (4/9) mutations were in Exon 2, both of which are principal coding exons for this gene.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Germany.
Objectives: This study aimed to evaluate the diagnostic utility of [Ga]Ga-DOTA-Siglec-9 positron emission tomography-computed tomography (PET/CT) in assessing disease activity in a patient experiencing a relapse of giant cell arteritis (GCA).
Case Presentation: A 90-year-old male patient with GCA, diagnosed in 2018, was enrolled. Demographic data, disease history, and laboratory parameters, including soluble VAP-1 (sVAP-1) levels, were recorded.
Clin Case Rep
January 2025
Department of Neurosurgery, School of Medicine Yamagata University Yamagata Japan.
A 46-year-old NF1 patient with sudden visual disturbance had a thrombotic vertebral artery aneurysm causing cerebral infarction. Endovascular internal trapping was performed successfully, with complete recovery and no neurological deficits. Although this is a rare case, it suggests that endovascular therapy could be successful for vascular lesions complicated by NF1.
View Article and Find Full Text PDFJ Clin Neurosci
January 2025
Department of Neurovascular Research, Kobe City Medical Center General Hospital, 2-1-1 Minatojima Minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan; Department of Neurosurgery, Seijinkai Shimizu Hospital, 11-2 Yamadanakayoshimicho, Nishikyo-ku, Kyoto, Japan.
Background: Past studies have reported that vertebrobasilar dolichoectasia (VBD) patients may develop similar arteriopathies other than the vertebrobasilar system. However, the details of these VBD-related arteriopathies are still unclear.
Methods: We retrospectively enrolled patients diagnosed with VBD at two stroke centers in Japan between January 2012 and December 2023.
Surg Radiol Anat
January 2025
Ovidius" University From Constanţa, Constanța, Romania.
Purpose And Background: The trigeminal artery is a rare anatomical variant, representing an embryonic vestige of the anastomosis between the internal carotid artery and the posterior circulator system, that can be asymptomatic or could have vast clinical manifestations produced by insufficient flow or by vascular nervous conflicts. This study is an anatomical presentation of 3 trigeminal artery cases observed at Medimar Imagistic Services Constanta.
Methods: The 3 trigeminal artery cases were discovered on a 860 magnetic resonance angiographies (0.
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