AI Article Synopsis

  • Extranodal extension (ENE) is a common feature in head and neck squamous cell carcinoma (HNSCC) that signifies tumor aggressiveness and raises the likelihood of local recurrence and distant metastasis.
  • ENE is utilized as a crucial indicator for prognosis and treatment decisions, yet there's a lack of consistent diagnostic standards for its assessment.
  • The article evaluates recent advancements in understanding the prognostic implications and diagnostic methods (both pathologic and radiologic) related to ENE in HNSCC.

Article Abstract

The extranodal extension(ENE) is widely found in head and neck squamous cell carcinoma(HNSCC), which displays the aggressiveness of the tumor and increasing the risk of local recurrence and distant metastasis, so the ENE often has been used as an important indicator of prognosis and treatment. Although the pathologic and radiologic tests are currently the main diagnostic techniques for ENE, there is still a lack of uniform standards. The article reviews the prognostic value, pathologic and radiologic diagnosis of ENE in HNSCC over the recent years.

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http://dx.doi.org/10.13201/j.issn.2096-7993.2024.12.020DOI Listing

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