AI Article Synopsis

  • The study investigates the relationship between two features in Intracerebral Hemorrhage (ICH), the spot sign and the blend sign, aiming to clarify the mechanisms behind their formation.
  • Researchers categorized patients based on the location of the spot sign within the blend sign and analyzed its association with hematoma expansion (HE) over a period from 2018 to 2023.
  • Results showed that the majority of patients with a spot sign had it in the hyperdensity region, and this was a strong predictor of HE, suggesting that the hyperdensity area indicates active bleeding.

Article Abstract

Background: Controversies still exist regarding the mechanism formation of the blend sign, defined as hypodensity and hyperdensity regions, in Intracerebral Hemorrhage (ICH), and which region associated with bleeding remains unknown. Spot sign is an independent predictor of hematoma expansion (HE) and indicates persistent bleeding focus in the hematoma. Here, we sought to establish the relationship between the spot sign and the blend sign to gain insights into the formation of the blend sign.

Methods: Patients were categorized based on the spot sign location within the blend sign in patients with ICH from 2018 to 2023. subjects with a spot sign in the hypodensity region of the blend sign (hypo-spot sign group); subjects with a spot sign in the hyperdensity region of the blend sign (hyper-spot sign group). Subsequently, patients were stratified into two groups based on the presence or absence of HE. Also, we analyzed the relationship between the spot sign and the blend sign, as well as the association between the blend sign and HE.

Results: A total of 205 patients were included, including 190 patients (92.7%) who had the spot sign in the hyper-spot sign and 15 patients (7.3%) who had the spot sign in the hypo-spot sign. HE was observed in 60 patients (29.3%), 59 (98.3%) of whom had the spot sign detected in the hyper-spot sign, while only one (1.7%) had the spot sign in the hypo-spot sign. Univariate logistic regression analysis revealed that the hyper-spot sign group (6.305, 1.810-49.072; P < 0.05) was an independent predictor of HE.

Conclusion: The hyperdensity area of the blend sign may represent fresh bleeding in ICH rather than the hypodensity area.

Download full-text PDF

Source
http://dx.doi.org/10.2174/0115734056310498241017052529DOI Listing

Publication Analysis

Top Keywords

spot sign
40
blend sign
36
sign
26
hyper-spot sign
16
sign hypo-spot
12
hypo-spot sign
12
sign group
12
blend
10
spot
10
fresh bleeding
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!