Department of Oral and Maxillofacial Surgery and Cochrane Associated Center at Faculty of Dentistry, University of Chile, Santiago, Chile. Electronic address:
Published: November 2024
AI Article Synopsis
Article Abstract
The aim of this study was to assess the evidence gaps identified in a recent mapping review of orthognathic surgery by evaluating them through consultation with maxillofacial surgeons. Using the Delphi technique, a panel of surgeons who regularly perform orthognathic surgery was engaged. Potential participants were identified through articles included in the mapping review, peer nominations, and social media platforms . Two rounds of surveys, incorporating Likert-type and open-ended questions, were conducted to gauge the clinical relevance of evidence gaps. Questions were refined based on responses from the initial round, with a consensus threshold set at 60%. Seventy-four surgeons participated in the first round and 55 in the second round (retention rate of 74%) . The intra-class correlation analysis revealed 'almost perfect' agreement in each round. Participants in the first round proposed 11 new evidence gaps. A list of 15 potentially clinically relevant research questions was compiled to guide future investigations in orthognathic surgery. This collaborative Delphi study between researchers and clinicians has explored the existing understanding of the clinical relevance of potential evidence gaps in orthognathic surgery. The study findings offer others a pathway to address information gaps and guide future research endeavours.
Background: The mental health system in Greece faces challenges to complete its transition to a community-oriented model, having significant concerns for child and adolescent care due to lower coverage and service gaps. This component of the mental health system has not been comprehensively evaluated.
Methods: We conducted a review of the mental health care system for children and adolescents in Greece.
Parkinson's disease (PD) is primarily recognized for its motor symptoms, yet non-motor symptoms (NMS) such as neuropsychiatric disturbances, sleep disorders, autonomic dysfunction, and sensory abnormalities significantly contribute to the disease's overall burden. While traditional pharmacological and surgical treatments have primarily targeted motor symptoms, alternative therapies such as acupuncture, cognitive therapy, and Traditional Chinese Medicine (TCM) are gaining attention for managing NMS. This review provides a comprehensive analysis of alternative therapies for NMS in PD, drawing on evidence from international guidelines and TCM.
Experts expressed severe concerns over the possibility of increasing burden of infectious diseases as the planet's climate began to change years ago. There have been increased rates of climate-related catastrophes and as global temperatures rise, emergence of certain viruses has become a serious concern. Vectors are susceptible to changing temperatures as they exhibit innate responses to thermal stress to increase survivability.
Introduction: Accumulating research suggests both eating disorders (EDs) and internalizing disorders (e.g., anxiety, depression) are associated with gastrointestinal disease (e.
Amadori compounds (ACs) are key intermediates of the Maillard reaction, and found in various thermally processed foods. Simultaneous analysis of multiple ACs is challenging due to the complex amino acid and carbohydrate compositions, and the different food matrices. Most studies focus on the effects of ACs on food flavor and related sensory properties, but not their biological functions.
