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http://dx.doi.org/10.1016/j.abd.2024.04.008 | DOI Listing |
Am J Dermatopathol
December 2024
Department of Dermatology, Vagelos College of Physician and Surgeons of Columbia University and New York Presbyterian Hospital, New York, NY; and.
Primary cutaneous amoebiasis is rare, and typically affects immunocompromised patients and presents with unique clinical and histopathologic changes. Untreated, the infection could progress to involve the central nervous system, which is almost universally fatal. We present a case of primary cutaneous acanthamoebiasis in a patient with chronic lymphocytic leukemia on acalabrutinib.
View Article and Find Full Text PDFAn Bras Dermatol
November 2024
Clinic of Dermatology, Santa Casa de São Paulo Hospital, São Paulo, SP, Brazil; Laboratory of Pathology, Santa Casa de São Paulo Hospital, São Paulo, SP, Brazil.
Pathogens
October 2024
Parasitology Laboratory, Department of Medical Biology, Medical University of Warsaw, Litewska 14/16, 00-575 Warsaw, Poland.
Front Cell Infect Microbiol
June 2024
Research and Development Department, Sinopharm Medical Laboratory (Wuhan) Co., Ltd., Wuhan, China.
Pathogenic and free-living are widely distributed in the environment and have been reported to cause keratitis and universally fatal encephalitis. Primary cutaneous acanthamoebiasis caused by is exceedingly rare and presents as isolated necrotic cutaneous lesions without involvement of the cornea or central nervous system. Cutaneous acanthamoebiasis often occurs in immunocompromised patients and is likely overlooked or even misdiagnosed only by cutaneous biopsy tissue histopathological analysis.
View Article and Find Full Text PDFBMJ Case Rep
January 2024
Swedish Cancer Institute, Seattle, Washington, USA.
Cutaneous amebiasis is a rare clinical entity caused by the invasive protozoan parasite that can be readily diagnosed with skin biopsy if suspected. It presents as a rapidly progressive and destructive ulceration with necrosis. A man in his 40s with metastatic rectal cancer who underwent palliative abdominal perineal resection with end colostomy in his left lower quadrant and on systemic chemotherapy developed progressive breakdown of his peristomal skin unresponsive to antibiotics that was then diagnosed to be cutaneous amebiasis.
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