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Surgical Treatment of Hepatocellular Carcinoma Arising from Fontan-associated Liver Disease: A Report of Three Cases. | LitMetric

AI Article Synopsis

  • * All patients displayed significantly elevated levels of serum alpha-fetoprotein (AFP) and showed that HCC tumors were typically located in the liver's peripheral regions.
  • * The authors emphasize the importance of ongoing monitoring of AFP levels and abdominal imaging for patients with FALD to detect HCC early.

Article Abstract

We herein report three patients with Fontan-associated liver disease (FALD) who developed hepatocellular carcinoma (HCC). All three patients had very high serum alpha-fetoprotein (AFP) concentrations, and their HCCs were located in the peripheral areas of the liver. To identify the characteristics of FALD-HCC, we reviewed previously published case reports that included descriptions of imaging. This review revealed that FALD-HCC is generally located in the peripheral areas of the liver and AFP concentrations are usually high. Thus, it is important that follow-up of patients with FALD include repeated AFP concentrations and abdominal imaging.

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Source
http://dx.doi.org/10.2169/internalmedicine.4631-24DOI Listing

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