A robust body of research has demonstrated that adolescents' survival expectations are predictive of important facets of their young adult lives. Specifically, adolescent perceptions of a low chance of surviving to young adulthood are associated with worse physical and mental health, higher engagement in risky behaviors, and lower socioeconomic status in young adulthood. Using data from a nationally representative sample of adolescent participants in the National Longitudinal Study of Adolescent to Adult Health, the purpose of the present study is to extend this line of research by investigating if adolescents' survival expectations are associated with premature (ages 14-46) all-cause mortality risk in the United States. We further consider whether this relationship varies by sex. Our results show that in the overall sample, adolescents who perceive they have a 50% chance or less of surviving to age 35 have a higher risk of mortality relative to their peers who perceive they are almost certain they will survive to age 35 net of sex and race/ethnicity (HR = 1.66, 95% CI: 1.19-2.32); the magnitude of this risk is reduced in a stepwise manner with the inclusion of indicators for socioeconomic status, physical and mental health, risky behaviors and exposure to violence (fully adjusted model HR = 1.31, 95% CI: 0.94-1.82). In sex stratified models, we find that adolescents' perceptions of a lower chance of surviving to age 35 are strongly associated with higher premature mortality risk among female adolescents but not male adolescents. Our findings add to the body of literature that underscores the detrimental consequences of adolescents' low expectations for survival to young adulthood on life trajectories by demonstrating that these consequences extend to actual survival.
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http://dx.doi.org/10.1016/j.socscimed.2024.117548 | DOI Listing |
Ann Thorac Surg Short Rep
December 2024
Department of Cardiovascular Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Background: The effect of coronary artery bypass grafting (CABG) on cardiac function improvement remains controversial. Furthermore, recent evidence suggests that improvement in cardiac function after CABG does not improve life expectancy. This study aimed to examine whether CABG improved cardiac function and how this improvement influenced all-cause mortality and to compare patient prognosis according to preoperative cardiac function.
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September 2024
Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Background: Suitable tracheostomy timing after cardiac operation remains controversial; hence, this study compared the effectiveness of early and late tracheostomy after cardiac operation.
Methods: By using the nationwide administrative claims database in Japan, patients who underwent cardiac operation between April 2010 and March 2020 were identified and included in this study. In-hospital mortality, incidence of deep sternal wound infection, and ventilator-free days were analyzed and compared by dividing patients into 2 groups: an early group (patients who underwent tracheostomy 1-14 days postoperatively) and a late group (patients who underwent tracheostomy 15-30 days postoperatively).
Ann Hematol
January 2025
Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
The prognosis of adult T-cell leukemia/lymphoma (ATL) with primary central nervous system (CNS) involvement has been unclear since the advent of new therapies. Recently, we have shown that flow cytometric CD7/CADM1 analysis of CD4 + cells (HAS-Flow) is useful to detect ATL cells that are not morphologically diagnosed as ATL cells. We investigated the role of CNS involvement in ATL using cytology and HAS-Flow by analyzing cerebrospinal fluid (CSF) from 73 aggressive ATL cases.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Epidemiology and Biostatistics, Key Laboratory of Molecular Cancer Epidemiology, Key Laboratory of Prevention and Control of Human Major Diseases, Ministry of Education, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, 300060, China.
Severe obesity is often associated with inflammation and insulin resistance (IR), which expected to increase the risks of mortality and cancers. However, this relationship remains controversial, and it's unclear whether healthy lifestyles can mitigate these risks. The independent and joint associations of severe obesity (body mass index ≥ 35 m/kg), inflammation (C-reactive protein > 10 mg/L and systemic inflammation markers > 9th decile), and IR surrogates with the risks of all-cause mortality and all-site cancers, were evaluated in 163,008 participants from the UK Biobank cohort.
View Article and Find Full Text PDFAm J Perinatol
January 2025
Ob-gyn, University of Minnesota System, Minneapolis, United States.
Background: Obesity is associated with an increased risk of stillbirth and neonatal death. Since the publication of A Randomized Trial of Induction Versus Expectant Management (ARRIVE) in 2018, there was an increase in 39 weeks deliveries. The objective of this study was to evaluate the trends in perinatal mortality by BMI category from 2015 to 2020.
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