This study introduces an alternative strategy for evaluating antiparasitic persistence compounds in cattle hair by Direct Analysis in Real Time Mass Spectrometry (DART-MS). The developed DART-MS method aimed to determine fenthion, chlorpyrifos, and cypermethrin in cattle hair samples. DART-MS analyses were performed in positive ion mode, and parameters related to the DART source were evaluated. The analytical performance demonstrated the efficiency of the optimized DART-MS method for fenthion, chlorpyrifos, and cypermethrin quantification in the evaluated samples, meeting criteria for precision, accuracy and limits of detection. Overall, the DART-MS method provided a fast and efficient analysis for determination of antiparasitic agents in cattle hair, which contributes to the evaluation of drug administration protocols and dosage intervals, and aids the safety and advancement of the livestock sector.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697339 | PMC |
| http://dx.doi.org/10.1021/jasms.4c00422 | DOI Listing |
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Article Synopsis
- - This study aimed to analyze the long-term effects of cortisol and aldosterone in the hair of six female Holstein calves using ELISA, across 18 calves over three seasons.
- - Results showed that cortisol levels were higher in the back region (white hair) compared to other regions and colors, and spring values were significantly higher than those in summer.
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