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Vaccination Communication Strategies and Uptake in Africa: A Systematic Review.
Vaccines (Basel)
November 2024
Department of Media, University of Hertfordshire, Hatfield AL10 9AB, UK.
: African countries experience high rates of infectious diseases that are mostly preventable by vaccination. Despite the risks of infections and other adverse outcomes, vaccination coverage in the African region remains significantly low. Poor vaccination knowledge is a contributory factor, and effective communication is crucial to bridging the vaccination uptake gap.
View Article and Find Full Text PDFVaccination Education Deficits and Vaccine Hesitancy Among Healthcare Students in Japan: A Cross-Sectional Study.
Vaccines (Basel)
November 2024
Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.
Background/objectives: Healthcare professionals' (HCPs') accurate knowledge of and positive attitudes toward immunization greatly influence society's acceptance of it. Early and appropriate immunization education for HCP students is vital. This study aimed to understand current immunization education and vaccine hesitancy among medical, nursing, and pharmacy students in Japan.
View Article and Find Full Text PDFRecent Advancements in Imaging Techniques for Individual Extracellular Vesicles.
Molecules
December 2024
The United Graduate School of Agricultural Science, Gifu University, Gifu 501-1193, Japan.
Extracellular vesicles (EVs), secreted from most cells, are small lipid membranes of vesicles of 30 to 1000 nm in diameter and contain nucleic acids, proteins, and intracellular organelles originating from donor cells. EVs play pivotal roles in intercellular communication, particularly in forming niches for cancer cell metastasis. However, EVs derived from donor cells exhibit significant heterogeneity, complicating the investigation of EV subtypes using ensemble averaging methods.
View Article and Find Full Text PDFSignal Peptides and Their Fragments in Post-Translation: Novel Insights of Signal Peptides.
Int J Mol Sci
December 2024
Department of Neurotoxicology, Graduate School of Medical Sciences and Medical School, Nagoya City University, Nagoya 467-8601, Japan.
Signal peptides (SPs), peptide sequences located at the N-terminus of newly synthesized proteins, are primarily known for their role in targeting proteins to the endoplasmic reticulum (ER). It has traditionally been assumed that cleaved SPs are rapidly degraded and digested near the ER. However, recent evidence has demonstrated that cleaved SP fragments can be detected in extracellular fluids such as blood flow, where they exhibit bioactivity.
View Article and Find Full Text PDFMicroRNA and Heart Failure: A Novel Promising Diagnostic and Therapeutic Tool.
J Clin Med
December 2024
Cardio Thoracic and Vascular Department, 'S. Maria alle Scotte Hospital', University of Siena, 53100 Siena, Italy.
Heart failure (HF) has a multifaceted and complex pathophysiology. Beyond neurohormonal, renin-angiotensin-aldosterone system, and adrenergic hyperactivation, a role for other pathophysiological determinants is emerging. Genetic and epigenetic factors are involved in this syndrome.
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