Research Progress on Sesquiterpenes from the Genus .

Molecules

School of Chemistry and Chemical Engineering, North Minzu University, Yinchuan 750021, China.

Published: November 2024

Sesquiterpenes constitute the principal components of the genus , encompassing guaiane, germacrane, eudesmane, and polymer sesquiterpene lactones types. These secondary metabolites exhibit diverse pharmacological activities, including antitumor, antibacterial, anti-inflammatory, antiviral, antioxidant, hepatoprotective, and neuroprotective effects. Through a comprehensive literature search of the Web of Science, PubMed, SciFinder, and CNKI databases, it was discovered that there are as many as 145 main sesquiterpenoids in the genus . However, the nuclear magnetic resonance (NMR) data for the sesquiterpenes in this genus have not been systematically compiled and summarized. Therefore, this review aims to highlight the chemical structures, NMR data, and pharmacological activities of sesquiterpenes in . By meticulously analyzing published scholarly literature, our goal is to provide a solid foundation for further exploration of new sesquiterpenes and extensive utilization of this genus.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11597153PMC
http://dx.doi.org/10.3390/molecules29225483DOI Listing

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