New approaches for the synthesis of organic thio- and selenocyanates, and methods to incorporate them into more complex structures, including a wide variety of heterocyclic and polycylic derivatives, are reviewed. Protocols that convert the SCN and SeCN moieties into the thio and seleno derivatives by transforming the cyano group are also examined. In representative cases, the bioactivity data for these classes of compounds are reviewed.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11596349PMC
http://dx.doi.org/10.3390/molecules29225365DOI Listing

Publication Analysis

Top Keywords

synthesis organic
8
advances synthesis
4
organic thiocyano
4
thiocyano scn
4
scn selenocyano
4
selenocyano secn
4
secn compounds
4
compounds chemical
4
chemical transformations
4
transformations bioactivity
4

Similar Publications

Recent Advances in Synthetic Strategies of Glycans and their Pharmaceutical Applications.

Curr Med Chem

January 2025

Sorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, UMR 8232, 4 Place Jussieu, 75005-Paris, France.

The understanding of glycans, the third life chain, is widely desired. Naturally, the glycoconjugates are found in heterogeneous forms due to the enzyme competition in the same process. As a result, the synthesis of homogeneous glycans has become one of the trending research topics.

View Article and Find Full Text PDF

Toxic organic solvents and electrolytes, traditionally indispensable for electro-organic synthesis, are now being reconsidered. In developing more sustainable electro-organic synthesis, we've harnessed the aqueous micelles as solvents and electrolyte-like structures when deformed under an electric field. The technology is showcased in synthetically highly valued hydrodefluorination reactions of difluorinated indoles.

View Article and Find Full Text PDF

Due to the industry's rapid growth, the presence of organic pollutants, especially antibiotics, in water and wastewater resources is the main concern for wildlife and human health. Therefore, these days, a significant challenge is developing an efficient, sustainable, and eco-friendly photocatalyst. Natural biological models have numerous advantages compared to artificial model materials.

View Article and Find Full Text PDF

Ecotoxicology of cephalopod early life phases: review and perspectives.

Environ Sci Pollut Res Int

January 2025

Instituto Politécnico Nacional, Centro Interdisciplinario de Ciencias Marinas, Av. Instituto Politécnico Nacional S/N, Playa Palo de Santa Rita, C.P. 23096, La Paz, Baja California Sur, Mexico.

The present review provides the first analysis and synthesis of the available scientific information on the effects of anthropogenic contaminants on cephalopod embryos, paralarvae, and juveniles. We evaluated 46 articles published between 1970 and 2023 that focused on trace elements (69%), pharmaceutical compounds (11%), persistent organic compounds (11%), and plastics (9%). To date, the greatest scientific effort has originated from Europe and Asia (France [57%], China [9%], Italy [7%], and Spain [4%]), with few reports available from the rest of the world.

View Article and Find Full Text PDF

3D Printing Organogels with Bioderived Cyrene for High-Resolution Customized Hydrogel Structures.

Langmuir

January 2025

Surface Science and Bio-nanomaterials Laboratory, Department of Chemical Engineering, University of Waterloo, Waterloo, Ontario N2L 3G1 Canada.

3D printing techniques are increasingly being explored to produce hydrogels, versatile materials with a wide range of applications. While photopolymerization-based 3D printing can produce customized hydrogel shapes and intricate structures, its reliance on rigid printing conditions limits material properties compared to those of extrusion printing. To address this limitation, this study employed an alternative approach by printing an organogel precursor using vat polymerization with organic solvents instead of water, followed by solvent exchange after printing to create the final hydrogel material.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!