Sports medicine has become a well-established field with a wide range of applications, from competitive and professional athletics to general well-being [...].
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| http://dx.doi.org/10.3390/life14111392 | DOI Listing |
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Malate initiates a proton-sensing pathway essential for pH regulation of inflammation.
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Department of Orthopedic Surgery/Sports Medicine Center, Southwest Hospital, Army Medical University, Chongqing, 400038, China.
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Oasis Diagnostics® Corporation, Vancouver, Washington, USA.
There is a pressing need for accessible biomarkers with high diagnostic accuracy for Alzheimer's disease (AD) diagnosis to facilitate widespread screening, particularly in underserved groups. Saliva is an emerging specimen for measuring AD biomarkers, with distinct contexts of use that could complement blood and cerebrospinal fluid and detect various analytes. An interdisciplinary, international group of AD and related dementias (ADRD) researchers convened and performed a narrative review of published studies on salivary AD biomarkers.
View Article and Find Full Text PDFUltrasound-Guided Intraosseous Injection of Bone Marrow Aspirate Concentrate for a Basketball Player With Bilateral Tibial Nonunion Fractures.
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Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, Georgia.
We present a case of a professional basketball player who suffered from nonunion bilateral chronic tibial fractures, successfully treated with ultrasound-guided intraosseous injection with bone marrow aspirate concentrate. The patient was able to return to play full time after recovery from the procedure.
View Article and Find Full Text PDFEffect of Linalool, Cineole, and β-Bourbonene Coupled with Aerobic Training on the Improvement of Presenilin-1/Amyloid Protein Precursor/Interleukin-1 beta/CASPASE 1 Network, Oxidative Capacity, and miRNA-210 in Mice with Alzheimer's Disease.
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Department of Sports Physiology, Faculty of Sports Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
Alzheimer's is an advanced nervous disorder related to aging. The present study aimed to determine the effect of eight-week aerobic training, along with the consumption of Linalool, Cineole, and β-Bourbonene, on the prevention and improvement of Alzheimer's disease. Mice were randomly assigned to 8 groups: control group, mice induced with Alzheimer's disease treated with β-amyloid (Alzheimer group), Alzheimer's mice treated with bioactive compounds of herbal medicine (Linalool with a concentration of 25 mg/kg, Cineole with a concentration of 100 mg/kg, and β-Bourbonene with a concentration of 10 μg/ml) by gavage for 8 weeks (Alzheimer+Biocompounds group), Alzheimer's mice treated with aerobic exercise with a moderate intensity treadmill for 8 weeks (Alzheimer's+Training group), Alzheimer's mice treated with bioactive compounds of herbal medicine and aerobic exercise for 8 weeks (Alzheimer+Biocompounds+Training group), healthy mice initially treated with bioactive compounds of herbal medication (Linalool with a concentration of 25 mg/kg, Cineol with a concentration of 100 mg/kg, and β-Bourbonene with a concentration of 0.
View Article and Find Full Text PDFCirc-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes.
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December 2024
Department of Rehabilitation Medicine, Wuhan No.1 Hospital, 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, China.
Background: Osteoarthritis (OA) is a common degenerative joint disease. Circular RNA Phosphodiesterase 1 C (circ-PDE1C, hsa_circ_0134111) has participated in the IL-1β-induced chondrocyte damages. The objective of our study was to explore the molecular mechanism of circ-PDE1C.
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