Hybrid Power Switches (HPS) combine the advantages of SiC unipolar and Si bipolar devices and therefore can bridge the gap between these technologies. In this paper, the performance of a hybrid power switch configuration based on the latest SiC MOSFET and Si IGBT technologies is presented. The device is evaluated through experimental measurements of its characteristics under various conditions. The results show the HPS can achieve switching losses as low as a SiC MOSFET while offering the high current capability of the IGBT without significant increase in costs.
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http://dx.doi.org/10.3390/mi15111337 | DOI Listing |
Comput Methods Biomech Biomed Engin
January 2025
Department of Clinical Surgery, Cty Clin Emergency Hosp, Sibiu, Romania.
This study examines heat transfer and nanofluid-enhanced blood flow behaviour in stenotic arteries under inflammatory conditions, addressing critical challenges in cardiovascular health. The blood, treated as a Newtonian fluid, is augmented with gold nanoparticles to improve thermal conductivity and support drug delivery applications. A hybrid methodology combining finite element method (FEM) for numerical modelling and artificial neural networks (ANN) for stability prediction provides a robust analytical framework.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Peking University, College of Chemistry and Molecular Engineering, Chengfu Road No.292, 100871, Beijing, CHINA.
Organic-inorganic hybrid perovskites have demonstrated great potential for flexible optoelectronic devices due to their superior optoelectronic properties and structural flexibility. However, mechanical deformation-induced cracks at the buried interface and delamination from the substrate severely constrain the optoelectronic performance and device lifespan. Here, we design a two-site bonding strategy aiming to reinforce the mechanical stability of the SnO2/perovskite interface and perovskite layer using a multifunctional organic salt, 4-(trifluoromethoxy)phenylhydrazine hydrochloride (TPH).
View Article and Find Full Text PDFMed Res Rev
January 2025
Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Targeted protein degradation (TPD) has emerged as a significant therapeutic approach for a variety of diseases, including cancer. Advances in TPD techniques, such as molecular glue (MG) and lysosome-dependent strategies, have shown substantial progress since the inception of the first PROTAC in 2001. The PROTAC methodology represents the forefront of TPD technology, with ongoing evaluation in more than 20 clinical trials for the treatment of diverse medical conditions.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
January 2025
Mund-Lagowski Department of Chemistry and Biochemistry, Bradley University, Peoria, Illinois 61625, United States.
In this communication we report the construction of a printed circuit board which mounts directly to the vacuum chamber of a mass spectrometer and produces the RF waveforms needed by many nonmass-selective devices such as ion guides and ion funnels. Our device is designed to replace a standard KF40 flange, can maintain vacuum chamber pressures of less than 10 Torr, and contains the circuitry of the open-source Wisconsin Oscillator RF power supply to generate RF waveforms of 1-4 MHz and up to 200 V. In this iteration of the Wisconsin Oscillator, we also introduce a variable resistor to control the output RF amplitude and show that its ion transmission capabilities are identical to those provided by commercial RF power supplies.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Chinese Academy of Sciences Fujian Institute of Research on the Structure of Matter, State Key Laboratory of Structural Chemistry, Yangqiao West Road 155, GuLou District, 350002, Fuzhou, CHINA.
Precise stacking of distinct two-dimensional (2D) rigid slabs to build heterostructures has renewed the portfolio of 2D materials, e.g., magic-angle graphene, due to the emergence of exotic physical properties.
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