AI Article Synopsis
- - The complexity of diabetes and its complications makes treating diabetic wounds difficult, prompting the need for new strategies.
- - Mesenchymal stem/stromal cells (MSCs) are being researched as a promising treatment for chronic wounds in diabetic patients, focusing on their ability to aid tissue regeneration.
- - This article discusses how MSCs can help treat diabetic foot ulcers, highlighting their mechanisms, the challenges faced in clinical applications, and the future of this research.
Article Abstract
The treatment of diabetic wounds is impaired by the intricate nature of diabetes and its associated complications, necessitating novel strategies. The utilization of mesenchymal stem/stromal cells (MSCs) as a therapeutic modality for chronic and recalcitrant wounds in diabetic patients is an active area of investigation aimed at enhancing its therapeutic potential covering tissue regeneration. The threat posed to the patient and their environment by the presence of a diabetic foot ulcer (DFU) is so significant that any additional therapeutic approach that opens new pathways to halt the progression of local changes, which subsequently lead to a generalized inflammatory process, offers a chance to reduce the risk of amputation or even death. This article explores the potential of MSCs in diabetic foot ulcer treatment, examining their mechanisms of action, clinical application challenges, and future directions for research and therapy.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11594847 | PMC |
| http://dx.doi.org/10.3390/ijms252212171 | DOI Listing |
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