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Traumatic Brain Injury as a Public Health Issue: Epidemiology, Prognostic Factors and Useful Data from Forensic Practice. | LitMetric

AI Article Synopsis

  • Traumatic brain injury (TBI) is a significant public health issue, particularly affecting young people, with high rates of disability and mortality across all age groups in developed countries.
  • The review explores the epidemiology and socioeconomic impact of TBI, emphasizing the importance of autopsy and histological methods for accurate diagnosis and understanding injury timing in forensic medicine.
  • It highlights the potential of brain injury biomarkers to enhance clinical predictions and improve management strategies, ultimately helping to reduce healthcare costs and improve outcomes for TBI patients.

Article Abstract

Traumatic brain injury (TBI) represents a major public health problem, being a leading cause of disability and mortality among young people in developed countries. Head trauma occurs across all age groups, each experiencing consistently high rates of mortality and disability. This review aims to present an overview of TBI epidemiology and its socioeconomic impact, alongside data valuable for prevention, clinical management, and research efforts. A narrative review of TBI was performed with a particular focus on forensic pathology and public health. In fact, this review highlighted the economic and epidemiological aspects of TBI, as well as autopsy, histology, immunohistochemistry, and miRNA. These data, together with immunohistochemical markers, are crucial for histopathological diagnosis and to determine the timing of injury onset, a fundamental aspect in forensic pathology practice. There is compelling evidence that brain injury biomarkers may enhance predictive models for clinical and prognostic outcomes. By clarifying the cause of death and providing details on survival time after trauma, forensic tools offer valuable information to improve the clinical management of TBI and guide preventive interventions. TBI is one of the most common causes of death today, with high costs for health care spending. Knowing the different mechanisms of TBI, reduces health care costs and helps improve prognosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11593823PMC
http://dx.doi.org/10.3390/healthcare12222266DOI Listing

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