AI Article Synopsis
- - PCOS is a common endocrine disorder in women marked by hormonal imbalances and reproductive issues, diagnosed through clinical evaluation and the Rotterdam criteria.
- - Its causes include genetic, environmental, and lifestyle factors that lead to issues like high androgen levels, insulin resistance, and chronic inflammation, affecting both reproductive and skin health.
- - The review focuses on how androgens contribute to skin conditions in PCOS, aiming to improve understanding and develop better treatment strategies for affected patients.
Article Abstract
Polycystic ovary syndrome is a presvalent endocrine disorder affecting women globally, characterized by hormonal imbalance, metabolic disturbances, and reproductive dysfunction. Diagnosis relies on clinical evaluation, medical history assessment, physical examination, and laboratory tests, with the Rotterdam criteria being widely used. The pathophysiology of PCOS involves genetic predisposition, environmental factors, and lifestyle influences, with hormonal dysregulation, particularly elevated androgens, insulin resistance, and chronic inflammation, playing a pivotal role. These mechanisms not only contribute to reproductive and metabolic disturbances but also to the various cutaneous manifestations, such as acne, hirsutism, and alopecia. This review aims to analyze the role of androgens in the dermatological manifestations in patients with polycystic ovary syndrome, providing insights into underlying mechanisms and guiding the development of effective therapeutic strategies. By synthesizing available evidence, this review aims to deepen understanding of related dermatological manifestations and improve outcomes for affected individuals.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11592971 | PMC |
| http://dx.doi.org/10.3390/diagnostics14222578 | DOI Listing |
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