Wood bleach is >95 % oxalic acid formulation used off-label as a miticide for Varroa mites by hobbyist beekeepers. Wood bleach (oxalic acid) ingestions are poorly documented in the medical literature. A 46-year-old man presented to the emergency department nauseated and vomiting after accidentally ingesting "bleach and grain ethanol intended for use in beekeeping." Initial evaluation was reported to the regional Poison Center as a creatinine concentration of 2.46 mg/dL (217 μmol/L); he was otherwise well. He was volume resuscitated and discharged home without further evaluation. Four days later, he returned with worsening nausea and vomiting, endorsing ongoing intentional use of the mixture as an intoxicant. He was fully oriented, in no distress, with normal vital signs but for blood pressure of 175/110 mmHg. Investigations revealed a serum creatinine of 16.8 mg/dL (1485 μmol/L) and a high anion gap metabolic acidosis (pH 7.3, bicarbonate 15 mmol/L, anion gap 29). Crystalluria testing was deferred due to anuria. Fomepizole, supplementary thiamine and pyridoxine were administered for suspected occult toxic alcohol poisoning; hemodialysis was initiated the same evening. Ethylene glycol resulted undetectable. Renal biopsy revealed oxalate nephropathy. It was revealed the mixture contained 'wood bleach,' or > 95 % oxalic acid, rather than reported sodium hypochlorite. Hemodialysis continued at 2-week follow-up. Presentations of anion gap metabolic acidosis in those who practice beekeeping should prompt consideration of oxalic acid toxicity. Early nephrology consultation may be needed to facilitate hemodialysis to prevent or treat metabolic acidosis and renal failure.
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http://dx.doi.org/10.1016/j.ajem.2024.11.052 | DOI Listing |
Int J Biol Macromol
January 2025
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China; Fujian Provincial Key Laboratory of Food Microbiology and Enzyme Engineering, Xiamen 361021, China; Research center of food biotechnology of Xiamen city, Xiamen, Fujian 361021, China. Electronic address:
In this study, polyethylene glycol 200 (PEG200) was employed as hydrogen bond acceptor, while organic acids served as hydrogen bond donors, to formulate poly-deep eutectic solvents (PDESs), which were utilized to pretreat tea stem. Specially, combining PEG200 and oxalic acid (OA) exhibited a notably high cellulose retention (82.03 %) and most efficient hemicellulose (97.
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April 2024
Department of Food Technology and Nutritional Science, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
Introduction: The misuse of antibiotics in poultry farming is a global issue.
Objective: The focus of this study was the health risk assessment of consumers from the determination of ciprofloxacin (CIP), tetracycline (TC), and oxytetracycline (OTC) in broiler chicken in the raw, frozen, and boiled stages using solid-phase extraction, high-performance liquid chromatography, and ultraviolet detection (SPE-HPLC-UV).
Materials And Methods: Chromatographic separation was achieved using 0.
Virulence
January 2025
The Key Laboratory for Extreme-Environmental Microbiology, College of Plant Protection, Shenyang Agricultural University, Shenyang, China.
Oxalic acid (OA), an essential pathogenic factor, has been identified in several plant pathogens, and researchers are currently pursuing studies on interference with OA metabolism as a treatment for related diseases. However, the metabolic route in remains unknown. In this study, we describe D-erythroascorbic acid-mediated OA synthesis and its metabolic and clearance pathways in rice blast fungus.
View Article and Find Full Text PDFDalton Trans
January 2025
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 211816, P. R. China.
In the history of magnetochemistry development, lanthanide-transition (3d-4f) heterometallic compounds have been considered an attractive candidate for magnetic refrigerants. Herein, a series of heterometallic compounds have been designed and templated by CO anions, that is, {[LnNi(L)(CO)(HO)]·HO} [Ln = Gd (. Gd2Ni) = Sm (.
View Article and Find Full Text PDFFoods
January 2025
Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510641, China.
Chlorine dioxide (ClO) gas has attracted considerable attention due to its safety and efficiency. In this study, we successfully developed a color-variable ClO slow-releasing card for postharvest litchi. The optimal ClO slow-releasing card was prepared as follows: Card A was soaked in 2.
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