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Demographic characteristics associated with a penicillin allergy label during pregnancy.

Front Allergy

December 2024

Section of Allergy and Immunology, Division of Pulmonary, Allergy and Critical Care Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Introduction: Penicillins and other beta-lactam antibiotics are used in greater than one-third of pregnant women as treatment for Group B Streptococcus colonization and prophylaxis for Caesarean sections. Penicillin allergy labels have been associated with increased morbidity in the pregnant population, and penicillin allergy evaluation during pregnancy is now recognized as safe and effective. Yet, demographic characteristics associated with having a penicillin allergy label during pregnancy have not been studied.

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Background/objectives: Stimulated cord blood mononuclear cell (CBMC) cytokine responses were previously shown to predict the risk of childhood atopic disease. Iron deficiency (ID) at birth may also program atopic disease. Males are at a higher risk of pediatric atopic disease, but it is not known whether congenital ID impacts CBMC immune responses differentially by sex.

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Early-Life Risk Factors and Clinical Features of Food Allergy Among Thai Children.

Int J Pediatr

October 2024

Division of Allergy and Immunology, Department of Pediatrics, Phramongkutklao Hospital and Phramongkutklao College of Medicine, 315 Rajavithi Road, Ratchathewi, Bangkok 10400, Thailand.

Food allergy affects 1%-10% of children under five worldwide, with genetic and early-life factors playing a primary role. Reported factors include a family history of allergic diseases, personal atopic dermatitis, cesarean section, dietary restrictions during pregnancy and lactation, and the timing of introducing solid foods. This study was aimed at identifying various factors associated with food allergy and evaluate each food allergy's clinical features.

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Long-term health outcomes of children born by cesarean section: A nationwide population-based retrospective cohort study in Taiwan.

J Formos Med Assoc

October 2024

Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Department of Pediatrics, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address:

Article Synopsis
  • The study looked into the health effects of being born by cesarean section (CS) in Taiwan, as many babies are born this way.
  • It found that children born by CS had a higher chance of developing problems like asthma, allergies, and being overweight compared to those born naturally.
  • The results suggest that cesarean deliveries might be linked to these health issues, especially obesity, but food allergies weren't affected.
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