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Is it possible to maintain a plaque-free healthy brain by treadmill?
Neural Regen Res
November 2024
Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA.
Protostylid: Contributing and Aggravating Factor for Periodontitis.
Cureus
April 2024
Periodontology, Sri Aurobindo College of Dentistry, Indore, IND.
Clinicians should be well-versed in the anatomy, variations, and teeth anomalies. Developmental disturbances of the teeth can lead to alterations in size, shape, number, structure, and eruption of the teeth. Developmental disturbances can lead to germination, fusion, concrescence, dilaceration, talons, cusps, dens in dente, etc.
View Article and Find Full Text PDFAnalysis and culturing of the prototypic crAssphage reveals a phage-plasmid lifestyle.
bioRxiv
March 2024
Department of Genetics, Stanford University, Stanford, CA, USA.
The prototypic crAssphage () is one of the most abundant, prevalent, and persistent gut bacteriophages, yet it remains uncultured and its lifestyle uncharacterized. For the last decade, crAssphage has escaped plaque-dependent culturing efforts, leading us to investigate alternative lifestyles that might explain its widespread success. Through genomic analyses and culturing, we find that crAssphage uses a phage-plasmid lifestyle to persist extrachromosomally.
View Article and Find Full Text PDFMapping the Endothelial Cell -Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function.
Circulation
March 2021
Institute for Vascular Signalling (S-I.B., J.H., J.W., M.K.D., V.R., F.D.L., B.F., S.Z., A.K., A.F.O.J., I.F.), Goethe University, Frankfurt am Main, Germany.
Background: In vascular endothelial cells, cysteine metabolism by the cystathionine γ lyase (CSE), generates hydrogen sulfide-related sulfane sulfur compounds (HS), that exert their biological actions via cysteine -sulfhydration of target proteins. This study set out to map the "-sulfhydrome" (ie, the spectrum of proteins targeted by HS) in human endothelial cells.
Methods: Liquid chromatography with tandem mass spectrometry was used to identify -sulfhydrated cysteines in endothelial cell proteins and β3 integrin intraprotein disulfide bond rearrangement.
Cleansing efficacy of waist-shaped inter-dental brushes. A randomized-controlled crossover study.
J Clin Periodontol
January 2020
Department of Operative and Prosthetic Dentistry, Medical University of Innsbruck, Innsbruck, Austria.
Objective: To compare the cleansing efficacy of waist-shaped versus cylindric inter-dental brushes in patients receiving supportive periodontal therapy.
Materials And Methods: After sample size estimation, 20 periodontal maintenance patients diagnosed with periodontitis stage 3 were recruited. Brushing efficacy of waist-shaped and cylindric inter-dental brushes was evaluated in a randomized-controlled, examiner-blinded, two-period crossover study by assessment of the Turesky modification of Quigley-Hein plaque index (T-QHI) and the papillary bleeding index (PBI) at four sites per tooth.
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