Background: This study estimated avoided recurrences and treatment costs in patients with stage II-IIIA non-small cell lung cancer treated with adjuvant atezolizumab in five European countries over 10 years (2024-2034).
Materials & Methods: Recurrences and deaths were projected in the presence and absence of adjuvant atezolizumab. Inputs were from the literature with extrapolation of disease-free survival from the IMpower010 trial. Country-level direct costs of treating recurrences were estimated.
Results: Adjuvant atezolizumab prevented an estimated 4952 recurrences (2199 locoregional, 2753 metastatic) over 10 years (2024-2034), associated with €264 million savings in treatment costs across the five countries.
Conclusion: Adjuvant atezolizumab may provide a meaningful reduction in recurrences and associated treatment costs among patients with early non-small cell lung cancer in Europe.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633414 | PMC |
| http://dx.doi.org/10.1080/1750743X.2024.2429958 | DOI Listing |
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