Objective: Our primary objective was to evaluate the interpregnancy interval (IPI) of women who have experienced obstetric anal sphincter injuries during delivery. Additionally, we compared adverse perinatal outcomes in subsequent deliveries following obstetric anal sphincter injuries (OASIS) in women with longer and shorter IPIs.
Methods: This retrospective cohort study included women who had a subsequent pregnancy following OASIS and women without a history of such injuries, who delivered in a tertiary medical center between 2015 and 2019. Data were retrieved from patient computerized medical records. Kaplan-Meier curves and Cox regression analysis were used to evaluate the IPI defined as the time from delivery to the last menstruation prior to the subsequent delivery. Data analysis for our secondary objective was performed using mean and standard deviation for quantitative variables.
Results: During the study period, 233 women experienced OASIS (0.27%), of whom 142 met the study criteria. There was no significant difference in the mean IPI between women in the two groups. However, women were significantly more likely to have a repeat perineal tear (49 [34.5%], P < 0.001), an episiotomy (16 [11.3%], P < 0.001), and an elective or an emergency cesarean section (60 [42.3%], P < 0.001) in their subsequent delivery. There was no difference in pregnancy outcomes among women who had a long compared with a short IPI.
Conclusions: Women do not delay or avoid childbirth after experiencing OASIS. However, women are more likely to experience perineal tears, episiotomies, or a cesarean delivery in the subsequent pregnancy.
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http://dx.doi.org/10.1002/ijgo.16045 | DOI Listing |
Am J Gastroenterol
November 2024
Division of Neurogastroenterology/Motility, Medical College of Georgia, Augusta University, Augusta, Georgia.
Anorectal neuropathy causes anorectal dysfunction, yet it is poorly recognized. This stems from both a lack of understanding of the extrinsic and intrinsic innervation of the anorectum and tools for evaluation of neuronal function. Our objective was to provide an improved understanding of the neuronal networks of the anorectum and discuss its functional significance.
View Article and Find Full Text PDFAm J Physiol Gastrointest Liver Physiol
January 2025
Wake Forest Institute for Regenerative Medicine, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.
This study aimed to determine if local injection of CXCL12 reduces sphincter fibrosis, restores sphincter muscle content, vascularization, and innervation, and recruits progenitor cells in a rabbit model of anal sphincter injury and incontinence. Adult female rabbits were assigned to 3 groups: uninjured/no treatment (control), injured/treated (treated), and injured/no treatment (untreated) (n=4 each). Injured groups were anesthetized and a section of external anal sphincter was removed at the 9:00 o'clock position.
View Article and Find Full Text PDFUrogynecology (Phila)
December 2024
University of Pittsburgh, Pittsburgh, PA.
Importance: Wound complications after obstetric anal sphincter injury (OASI) can amplify morbidity and affect quality of life.
Objective: The objective of this study was to evaluate for characteristics associated with wound complications after OASI.
Study Design: This was a retrospective cohort study of patients with an OASI who were evaluated in a postpartum pelvic floor healing clinic between November 1, 2020, and May 16, 2023.
Front Surg
December 2024
Department of Anorectal Diseases, Shanghai Baoshan District Integrated Traditional Chinese and Western Medicine Hospital, Shanghai, China.
Background: The main goals of surgery for fistula-in-ano are to completely resolve the condition and maintain optimal anal function. Effective management of the internal opening during and proper postoperative drainage of the intersphincter plane are crucial for achieving successful outcomes. This study evaluated the clinical efficacy of a novel sphincter-sparing technique for treating high transsphincteric anal fistula (HTAF).
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Breast Surgery, General Surgery, Xiangya Hospital, Central South University, Changsha, China. Electronic address:
Background: There was limited evidence on the comparative value of various examination methods for women with obstetric anal sphincter injuries (OASIS).
Objectives: To evaluate diagnostic performance of different examination methods for detecting OASIS.
Methods: We searched PubMed, EMBASE, Cochrane Library, and Web of Science to identify relevant studies from inception to December 2023.
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