AI Article Synopsis
- The reaction describes how (bromodifluoromethyl)trimethylsilane (TMSCFBr) interacts with potassium thiocyanate to produce TMSCFNCS.
- The process involves difluorocarbene reacting with the nitrogen atom in the thiocyanate ion.
- The resulting silicon compound is used to introduce fluorinated groups into -alkyl imines, leading to the formation of 2-(difluoromethylthio)-4-fluoroimidazoles.
Article Abstract
The reaction between (bromodifluoromethyl)trimethylsilane (TMSCFBr) and potassium thiocyanate providing TMSCFNCS is described. The process involves the interaction of difluorocarbene with the nitrogen atom of the thiocyanate anion. The obtained silicon reagent served as a source of the fluorinated group and difluorocarbene in the reaction with -alkyl imines, affording 2-(difluoromethylthio)-4-fluoroimidazoles.
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