The heart is a remarkable organ from both a scientific and functional standpoint, as well as a symbolic representation of many noble elements of human concern found in poetry, art, and religion. Cinema, a form of art in and of itself, has also taken an interest in the heart. Recently, a TV series dedicated to this organ has combined historical research on the groundbreaking development of the possibility of curing it with the romantic element of the love affair that, in a figurative sense, passes through the same organ. About 75 years ago, cardiology began to evolve and culminate in cardiac surgery, which has since spread quickly throughout the globe, including Italy. Fiction is an enjoyable and easily accessible instrument that tells the tale of the creation and quick evolution of cardiology. It is undoubtedly a superb educational medium that helps both the younger and older generations learn about, understand, and value our heritage.
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[Heart and fiction: where historical reality ends and fantasy begins].
G Ital Cardiol (Rome)
December 2024
S.C. Cardiologia, Ospedale Mauriziano Umberto I, Torino.
The heart is a remarkable organ from both a scientific and functional standpoint, as well as a symbolic representation of many noble elements of human concern found in poetry, art, and religion. Cinema, a form of art in and of itself, has also taken an interest in the heart. Recently, a TV series dedicated to this organ has combined historical research on the groundbreaking development of the possibility of curing it with the romantic element of the love affair that, in a figurative sense, passes through the same organ.
View Article and Find Full Text PDFCost-effectiveness of Implementing a Genotype-Guided De-Escalation Strategy in Patients with Acute Coronary Syndrome.
Eur Heart J Cardiovasc Pharmacother
November 2024
Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Aims: A genotype-guided P2Y12-inhibitor de-escalation strategy, switching acute coronary syndrome (ACS) patients without a CYP2C19 loss-of-function allele from ticagrelor or prasugrel to clopidogrel, has shown to reduce bleeding risk without affecting effectivity of therapy by increasing ischemic risk. We estimated the cost-effectiveness of this personalized approach compared to standard dual antiplatelet therapy (DAPT; aspirin plus ticagrelor/prasugrel) in the Netherlands.
Methods And Results: We developed a one-year decision tree based on results of the FORCE-ACS registry, comparing a cohort of ACS patients who underwent genotyping with a cohort of ACS patients treated with standard DAPT.
Medicine Through the Lens of Humanity: Exploring the Legacy of Oliver Sacks, the Storyteller Neurologist.
Cureus
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Geriatrics, Northwell Health, Staten Island, USA.
Article Synopsis
- Dr. Oliver Sacks was a neurologist known for integrating a compassionate and patient-centered approach into medicine during a time when a more authoritarian style prevailed.
- He faced personal challenges such as prosopagnosia and conflicts related to his sexuality, using these experiences to enrich his understanding of neurology and create accessible narratives about neurological disorders through his literature.
- In his later years, Sacks focused on themes of mortality and life's purpose, advocating for a healthcare model that respects patients' personal values, leaving a lasting impact on medical practice and the connection between science and humanity.
Flying with nut and other food allergies: unravelling fact from fiction.
Arch Dis Child
December 2024
Aviation Medical Consultancy Limited, Burgess Hill, UK.
There is a common perception that peanut/tree nut particles can be transmitted through aircraft ventilation systems and pose a significant risk to passengers with food allergies. In fact, food-induced allergic reactions are around 10-100 times less common during flights than 'on the ground', perhaps because of the multiple precautions food-allergic passengers take when flying. We review the evidence for strategies to help prevent accidental allergic reactions while travelling on commercial flights (review registered at PROSPERO, ref CRD42022384341).
View Article and Find Full Text PDFHuman Papillomavirus as Nontraditional Cardiovascular Risk Factor: Fact or Fiction? Part 2.
Am J Med
December 2024
Cardiology Division, NYU Langone Health and NYU School of Medicine, New York, NY. Electronic address:
Human papillomavirus (HPV) is the most common sexually transmitted infection in the US and worldwide, with more than 42 million Americans infected with types of HPV that are known to cause disease. While the link between HPV and the development of a variety of cancers has been strongly established, recent literature has demonstrated a potential association between HPV and increased risk of cardiovascular disease. Nevertheless, despite plausible mechanisms for the development of cardiovascular disease with HPV infection, a causative relationship has yet to be firmly established, in part due to potential confounding risk factors between the two.
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