Dicyanovinyl-modified uracil produces fluorescent molecular rotors (FMR) that display massively red-shifted emission and huge Stokes shifts. They are exemplified by DCVSU - an intrinsically fluorescent nucleobase analog (IFNA) with the longest emission wavelength of 592 nm (DMSO) reported thus far which also shows strong polarity sensitivity and large Stokes shift ( = 181 nm). The IFNAs exhibited typical molecular rotor response to solvent viscosity with brightnesses ( × ) of up to 8700 cm M. H NMR titration confirmed the expected association of the IFNA with the complementary nucleobase adenine-9-ethyl acetate.
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| http://dx.doi.org/10.1039/d4ra07000c | DOI Listing |
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