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Unraveling the ancient fungal DNA from the Iceman gut.
BMC Genomics
December 2024
Faculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, Piazza Università 5, Bolzano, Italy.
Background: Fungal DNA is rarely reported in metagenomic studies of ancient samples. Although fungi are essential for their interactions with all kingdoms of life, limited information is available about ancient fungi. Here, we explore the possibility of the presence of ancient fungal species in the gut of Ötzi, the Iceman, a naturally mummified human found in the Tyrolean Alps (border between Italy and Austria).
View Article and Find Full Text PDFTyrolean Iceman's arrow injury to the shoulder: New insights into extent and survival time.
J Shoulder Elbow Surg
November 2024
Eurac Research, Institute for Mummy Studies, Bolzano, Italy.
The Tyrolean Iceman is known as one of the oldest human glacier mummies, directly dated to 3350-3120 calibrated BCE. A previously published low-coverage genome provided novel insights into European prehistory, despite high present-day DNA contamination. Here, we generate a high-coverage genome with low contamination (15.
View Article and Find Full Text PDFThe Equipment of the Tyrolean Iceman: Innovation versus Adaptation in the Cultural Evolution of Prehistoric Technologies.
J Anthropol Sci
June 2021
Institute of Psychology, University of Pécs, Ifjúság Str. 6. H-7624 Pécs, Hungary.
This study argues that the equipment of the Tyrolean Iceman offers a unique perspective for understanding the macroevolutionary-scale functional continuity between later Pleistocene and Holocene human technologies. The Iceman was discovered in 1991 in the Ötztal Alps and can be dated to around 3300 BC, corresponding to the North Italian early Copper Age. In his gear there are several technologies which are rarely found at prehistoric archaeological sites, including archery equipment, a complete set of clothing, and a personal tool kit.
View Article and Find Full Text PDFCholesterol Review: A Metabolically Important Molecule.
Endocr Pract
December 2020
From the (1)University of New Mexico School of Medicine, Department of Internal Medicine, Division of Endocrinology and Metabolism, Albuquerque, New Mexico, and the.
Objective: Cholesterol is an important molecule in humans and both its excess and its deficiency cause disease. Most clinicians appreciate its role in stabilizing cellular plasma membranes but are unaware of its myriad other functions.
Methods: This review highlights cholesterol's newly recognized important roles in human physiology and pathophysiology.
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