Objective: The systemic inflammation response index (SIRI) is a marker used to predict survival. The aim of this study is to examine the relationship between SIRI and clinicopathological features and survival.
Method: The relationship between clinicopathological characteristics and survey and SIRI was retrospectively investigated.
Results: A total of 178 patients were included in the study. Poor prognostic factors such as tumor size, t, T-stage, tumor-node-metastasis (TNM) stage, and CA19-9 level were found to have a statistically significant relationship with patients with high SIRI (p = 0.039, p = 0.001, p = 0.001 and p = 0.013, respectively). A high SIRI was found to be an independent and poor prognostic factor for 3-year and 5-year survival (p = 0.014 and p = 0.027, respectively).
Conclusions: High SIRI was associated with a poor survival rate, as were advanced TNM stage, advanced T stage, larger tumor size, and elevated CA19-9 level; all these are poor prognostic markers for gastric cancer.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.24875/CIRU.23000234 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
CD4FOXP3Exon2 regulatory T cell frequency predicts breast cancer prognosis and survival.
Sci Adv
January 2025
Istituto per l'Endocrinologia e l'Oncologia Sperimentale "G. Salvatore", IEOS-CNR, Napoli, Italy.
CD4FOXP3 regulatory T cells (T) suppress immune responses to tumors, and their accumulation in the tumor microenvironment (TME) correlates with poor clinical outcome in several cancers, including breast cancer (BC). However, the properties of intratumoral T remain largely unknown. Here, we found that a functionally distinct subpopulation of T, expressing the FOXP3 Exon2 splicing variants, is prominent in patients with hormone receptor-positive BC with poor prognosis.
View Article and Find Full Text PDFThe prognostic value of global longitudinal strain in patients with myocardial infarction and preserved ejection fraction - a prespecified substudy of the REDUCE-AMI trial.
Eur Heart J Cardiovasc Imaging
January 2025
Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.
Aims: The REDUCE-AMI trial showed that beta-blockers in patients with preserved left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) had no effect on mortality or cardiovascular outcomes. The aim of this substudy was to evaluate whether global longitudinal strain (GLS) is a better prognostic marker than LVEF, and if beta-blockers have a beneficial effect in patients with decreased GLS.
Methods And Results: REDUCE-AMI was a registry-based randomized clinical trial.
Evaluating the prognostic role of glucose-to-lymphocyte ratio in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors in first line: a study by the Turkish Oncology Group Kidney Cancer Consortium (TKCC).
Clin Transl Oncol
January 2025
Department of Medical Oncology, Ankara University School of Medicine, 06590, Ankara, Türkiye.
Purpose: Identifying prognostic indicators for risk stratification in metastatic renal cell carcinoma (mRCC) is crucial for optimizing treatment strategies and follow-up plans. This study aims to investigate the prognostic role of the glucose-to-lymphocyte ratio (GLR) in patients with mRCC receiving tyrosine kinase inhibitors (TKIs) as first-line therapy.
Methods: A retrospective cohort study was conducted using data from the Turkish Oncology Group Kidney Cancer Consortium Database.
Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma.
Discov Oncol
January 2025
Department of Orthopedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
Sarcoma (SARC), a diverse group of stromal tumors arising from mesenchymal tissues, is often associated with a poor prognosis. Emerging evidence indicates that senescent cells within the tumor microenvironment (TME) significantly contribute to cancer progression and metastasis. Although the influence of senescence on SARC has been partially acknowledged, it has yet to be fully elucidated.
View Article and Find Full Text PDFRepeatability of radiomic features in myocardial T1 and T2 mapping.
Eur Radiol
January 2025
Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Centre Rostock, Rostock, Germany.
Purpose: To investigate the test-retest repeatability of radiomic features in myocardial native T1 and T2 mapping.
Methods: In this prospective study, 50 healthy volunteers (29 women and 21 men, mean age 39.4 ± 13.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!