AI Article Synopsis
- A myxopapillary ependymoma (MPE) is a rare variant of ependymoma typically found in the conus medullaris or filum terminale, with very few cases documented in the brain, particularly in the fourth ventricle.
- A 31-year-old woman experienced balance issues and headaches, leading to MRI scans that revealed a tumor in the fourth ventricle, which resulted in obstructive hydrocephalus; surgical removal confirmed the tumor as MPE, classified as WHO grade 2.
- This case highlights the challenges posed by MPEs due to their tendency to adhere to and infiltrate surrounding neural tissue, impacting treatment outcomes, especially in cases located in the fourth ventricle.
Article Abstract
Background: A myxopapillary ependymoma (MPE) is a distinctive ependymoma variant that arises exclusively in the conus medullaris or the filum terminale. There are few case reports of intracranial occurrences, with even rarer occurrences in the fourth ventricle.
Observations: A 31-year-old female patient presented with difficulty in maintaining her balance and headaches of 3 months' duration. Brain magnetic resonance imaging showed a fourth ventricle mass with obstructive hydrocephalus. Surgical removal of the tumor was performed. The biopsy of the tumor revealed the histological feature of MPE, World Health Organization grade 2. To the authors' knowledge, this is the fourteenth reported case of primary intracranial MPE and the fifth reported case of MPE originating from the fourth ventricle.
Lessons: MPEs are known for their notorious adhesion and infiltration of adjacent neural tissue; therefore, the clinical outcome of fourth ventricle MPEs depends on their relationship with the floor of the fourth ventricle. https://thejns.org/doi/10.3171/CASE24571.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11605521 | PMC |
| http://dx.doi.org/10.3171/CASE24571 | DOI Listing |
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