AI Article Synopsis
- The aerosol challenge allows researchers to explore how viruses, particularly filoviruses like Marburg and Ebola, can be transmitted through the air and the risks involved.
- Studies using aerosol exposure help understand how these viruses progress, their harmful effects, and how effective medical treatments can be.
- This protocol focuses on outlining the methods for experimenting with aerosol exposure in animals infected with Marburg virus.
Article Abstract
Aerosol challenge provides the ability to investigate in-depth mucosal virus exposure, including modeling of airborne transmission from high-consequence viral infection. For filoviruses, in particular Marburg and Ebola viruses, aerosol infection is considered in connection to their potential misuse. Aerosol exposure with filoviruses has been used to study disease progression, pathogenicity, and the efficacy of medical countermeasures. The aim of this protocol is to provide a general outline for aerosol exposure of animals with filoviruses, specifically Marburg virus.
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| http://dx.doi.org/10.1007/978-1-0716-4256-6_21 | DOI Listing |
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