Purpose: Femoral shaft fractures with third fragments are difficult to reduce anatomically, affecting bone healing chances. The goal of this study is to determine the impact of the third fragment's radiological characteristics assessed on post-operative radiographs, as well as other factors, on the healing of type 32B femur shaft fractures treated with intramedullary nail.
Methods: We conducted a retrospective study of 93 patients treated for femoral shaft fractures type 32 B. On post-operative X-rays, two radiologic parameters were evaluated: the third fragment size and the mean third fragment displacement. Patients had radiologic follow-up at 2, 4, 6, 9, and 12-months and were separated into 3 groups based on their fracture healing time: within 6 months (group 1), between 6 and 12 months (group 2), or nonunion after 12 months (group 3).
Results: Among the 93 patients, 72 (77.4%) showed fracture healing at 6 months, 13 (14%) at 12 months, and 8 (8.6%) demonstrated nonunion at 12 months. The mean third fragment displacement was notably different between groups (p < 0.001) and was considerably greater in group 3 than in groups 1 and 2. The influence of third fragment displacement on outcomes under 6 months was determined by ROC analysis, using a cut-off value of 14 mm. Displacement under 14 mm predicted healing within 6 months with a sensitivity of 90.3% and a specificity of 61.9%. The statistical analysis demonstrated that the odds of experiencing non-union or delayed healing were approximately 15 times higher for patients with a third fragment displacement of 14 mm or greater.
Conclusion: The third fragment displacement is the most important factor influencing healing within twelve months in femur shaft fractures type 32B managed with an intramedullary nail. Inversely, the third fragment size had no effect on the healing of the fractures in our series.
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http://dx.doi.org/10.1007/s00590-024-04146-8 | DOI Listing |
Best Pract Res Clin Obstet Gynaecol
December 2024
University of California, San Francisco, Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Maternal-Fetal Medicine, 1825 Fourth St, Third Floor, San Francisco, CA, 94158, USA; University of California, San Francisco, Institute of Human Genetics, 1825 Fourth St, Third Floor, San Francisco, CA, 94158, USA. Electronic address:
Screening for fetal genetic disorders is a focus of prenatal care. Cell free DNA (cfDNA) screening for aneuploidies became available in 2011. Initially available only to high-risk individuals, this test is now standard of care in many settings.
View Article and Find Full Text PDFArch Orthop Trauma Surg
December 2024
Department of Orthopedic Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.
Introduction: Previous study did not clarify the correlation between the natural course of perioperative blood tests and occurrence of wound-related complications, including SSI, PJI, and delayed wound healing. This study aimed to investigate whether perioperative laboratory test is effective in identifying wound-related complications after THA.
Materials And Methods: This retrospective, single-institutional study enrolled 1072 patients who underwent primary THAs.
Surv Ophthalmol
December 2024
Ophthalmology Unit, IRCSS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy. Electronic address:
Inflammatory choroidal neovascularization (iCNV) significantly contributes to vision impairment and ranks as the third primary cause of CNV. Arising from both infectious and noninfectious uveitis, iCNV's pathogenesis involves Bruch membrane rupture, local inflammation, and choriocapillaris ischemia. The diagnosis of iCNV is challenging due to its symptomatic overlap with other uveitis-related conditions.
View Article and Find Full Text PDFStomatologiia (Mosk)
December 2024
Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia.
The main principles of management of children with root fractures of permanent teeth in the coronal third are presented using two clinical cases as an example. In the treatment of root fractures in the coronal third, an important condition for success is timely flexible or semi-flexible splinting of the tooth for a sufficiently long period (up to 4 months). In the absence of splinting or significant mobility of the coronal fragment after removal of the splint the probability of pulp necrosis is very high, and the method of choice is treatment with calcium silicate cements with their introduction by orthograde or surgical access.
View Article and Find Full Text PDFEnviron Sci Technol
December 2024
Department of Environmental Health Science, Yale School of Public Health, New Haven, Connecticut 06511, United States.
Per- and polyfluoroalkyl substances (PFAS) are widely used persistent synthetic chemicals that have been linked to adverse health effects. While the behavior of PFAS has been evaluated in the environment, our understanding of reaction products in mammalian systems is limited. This study identified biological PFAS transformation products and generated mass spectral libraries to facilitate an automated search and identification.
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