With the exploding number of IoT devices generating vast data volumes, there is a growing risk of significant performance degradation without efficient congestion management. To tackle this challenge, efficient regulation and supervision are essential for managing congestion in IoT networks. This research work introduces a One-Way-Delay (OWD)-based congestion control (CC) method that estimates data transmission delays of the communication path and adjusts network traffic accordingly. The proposed method enhances IoT device performance by continuously monitoring OWD along the transmission path to identify and mitigate congestion. Comparative analysis with existing methods demonstrates that the proposed approach more effectively utilizes network resources, reduces congestion, and improves throughput while ensuring fairness and reliability within the IoT infrastructure. The experimental simulations show that the proposed OWD-based method outperforms well-established TCP variants such as BBR, TCP Cubic, HTCP, and New Reno, achieving average throughput improvements ranging from 4.1 % to 22.7 %. The proposed method also maintains fairness in mixed-traffic environments and effectively manages congestion in complex network topologies.
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http://dx.doi.org/10.1016/j.heliyon.2024.e40266 | DOI Listing |
Clin Neuropharmacol
January 2025
Medical Biochemistry, Erzincan Binali Yıldırım University Faculty of Medicine, Erzincan, Turkey.
Objectives: Our aim was to evaluate the comparative effects of sertraline and vortioxetine against stress-induced brain injury in rats.
Methods: The rats were assigned to a nonstress group (NSG), stress-treated control (StC), sertraline + stress (SSt), and vortioxetine + stress (VSt) groups. Sertraline and vortioxetine (10 mg/kg) were given orally by gavage to the SSt and VSt groups.
Behav Brain Res
January 2025
Division of Biotechnology, School of Life Sciences, Manipal Academy of Higher Education, Manipal- 576104, India.
Whilst the world sees the tremendous growth of mobile phone technology, radiofrequency electromagnetic radiation (RF-EMR) induced possible health effects have emerged as a topic of recent day debate. The current study is designed to test the hypothesis that chronic 900MHz radiation exposure would potentially dysregulate the stress response system (HPA axis) in vivo, via, its non-thermal mechanisms, leading to alterations in the microarchitecture of the adrenal gland, vulnerable brain regions such as the hippocampus which may results in altered behaviours in rats. Male albino Wistar rats aged four weeks, weighing 50-60g were subjected to 900MHz radiation from a cellphone for four weeks at a rate of one hour per day.
View Article and Find Full Text PDFBMC Chem
January 2025
National Organization for Drug Control and Research (NODCAR), P.O.Box 29, Cairo, Egypt.
Tirofiban hydrochloride is used to inhibit platelet aggregation, which has a significant impact on the treatment of congestive heart failure the most common cause of death according to WHO. Therefore, its quantification in pharmaceutical dosage form is critical. In this work, an electrochemical method for the determination of tirofiban HCl in pharmaceutical dosage form was developed and validated.
View Article and Find Full Text PDFArch Osteoporos
January 2025
Department of Endocrinology and Diabetes, Xiamen Clinical Medical Center for Endocrine and Metabolic Diseases, Xiamen Diabetes Institute, The First Affiliated Hospital of Xiamen University, No. 55 Zhenhai Road, Xiamen, 361003, China.
Unlabelled: Our study investigated trends in osteoporosis management in Xiamen from 2012 to 2021, revealing improvements in screening and treatment, although medication use remained low. Additionally, we identified factors that may influence medication use and emphasized the importance of effective osteoporosis management strategies.
Purpose: The goal of the current study is to explore trends in assessment, diagnosis after fragility fractures, and osteoporosis treatment among hospitalized patients in Xiamen, China, between 2012 and 2021.
Medicina (Kaunas)
December 2024
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir 26040, Turkey.
The aim was to evaluate nerve healing using immunohistochemical, histological, and functional techniques and to compare the effects of two different therapeutic ozone application methods by perineural and intraperitoneal ozone treatment in rats with a crush injury model of sciatic nerve. Forty male Sprague Dawley rats were divided into four subgroups of ten rats each: (1) Control group: The left sciatic nerve incised and closed without crush injury, no treatment; (2) Paralyzed group: Crush injury to the left sciatic nerve, no treatment; (3) Perineural ozone group: Crush injury to the left sciatic nerve, treated with perineural ozone therapy; (4) Intraperitoneal ozone group: Crush injury to the left sciatic nerve, treated with intraperitoneal ozone therapy. The treatments were administered for a 14-day period.
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