Suprapubic catheterisation (SPC) is a commonly performed urological procedure. Although it is generally safe, SPC-induced bowel injury is a rare but morbid complication. It is described in the literature, but management consensus is lacking. A scoping review was conducted assessing existing literature regarding the management of intestinal injury. The review highlighted that bowel perforation, particularly involving the small bowel and terminal ileum, is the commonest SPC-related bowel injury type. Depending on the severity of the injury and the patients' condition, various management strategies, ranging from exploratory laparotomy to less invasive techniques like laparoscopic intervention, are documented. Despite the introduction of preventive measures, such as ultrasound guidance, intestinal injury occurs. SPC-associated bowel injury is a serious but rare complication despite available preventative measures. Its management varies and depends on the part of the bowel injured and its severity. This review highlights reported management strategies specific to this injury and a literature summary to aid future quality improvement on the topic.
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http://dx.doi.org/10.7759/cureus.74057 | DOI Listing |
Sci Rep
December 2024
Department of Medical Research, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Infectious intestinal diseases (IIDs) pose a significant health and economic burden worldwide. Recent observations at the Tri-Service General Hospital, Taiwan, suggest a potential association between IIDs and neurodegenerative diseases, prompting an investigation into this relationship. This study explored interactions between IIDs and neurodegenerative diseases.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address:
Ionizing radiation-induced injury often occurs in nuclear accidents or large-dose radiotherapy, leading to acute radiation syndromes characterized by hematopoietic and gastrointestinal injuries even to death. However, current radioprotective drugs are only used in hospitals with unavoidable side effects. Here, we heated the aqueous solution of inulin, a polysaccharide dietary fiber, forming colon-retentive gel as a radiation protector in radiotherapy.
View Article and Find Full Text PDFCell Immunol
December 2024
Defence Institute of Physiology and Allied Sciences, Delhi 110054, India. Electronic address:
The gastrointestinal (GI) tract is susceptible to damage under high altitude hypoxic conditions, leading to gastrointestinal discomfort and intestinal barrier injury. Sodium butyrate, a short-chain fatty acid present as a metabolite in the gut, has emerged as a promising therapeutic agent due to its ability to act as an immunomodulatory agent and restore intestinal barrier integrity. This study aimed to explore the mechanism by which sodium butyrate exhibits anti inflammatory effect on intestinal epithelial cells.
View Article and Find Full Text PDFRes Vet Sci
December 2024
College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. Electronic address:
To investigate the regulatory mechanisms and pathways of visfatin under immune stress injury in weaned piglets, we established a lipopolysaccharide-induced immune stress model in weaned piglets to study how visfatin affects peripheral immune organs and intestinal function. The results revealed that visfatin improved the inflammatory response in immune-stressed weaned piglets by reducing the levels of pro-inflammatory cytokines interleukin-1β, interleukin-6 and monocyte chemoattractant protein-1, as well as decreasing the neutrophil/lymphocyte ratio. Visfatin ameliorated oxidative stress in piglets by promoting the expression of superoxide dismutase and glutathione peroxidase.
View Article and Find Full Text PDFToxins (Basel)
November 2024
Key Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Aflatoxin B is a prevalent secondary hazardous metabolite generated by fungus present in feed ingredients and the surrounding environment: enzymes are currently being recognized as an efficient and promising approach to reducing the associated risks. The objective of this study was to assess the effects of varying doses of enzyme complexes on several parameters in laying hens that were exposed to aflatoxin. During an 8-week experiment, a total of 288 Yukou Jingfen No.
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