Tumoral calcinosis is a rare disorder characterized by the deposition of calcium phosphate crystals in periarticular soft tissues, often presenting as asymptomatic masses. However, these calcific masses can occasionally cause significant morbidity by compressing adjacent neurovascular structures. We report a rare case of tumoral calcinosis leading to peripheral nerve compression of the suprascapular nerve in a 55-year-old female. The patient presented with progressive shoulder pain and weakness, significantly affecting her daily activities. Imaging studies, including X-ray, CT, and MRI, revealed large, calcified masses in the scapular region compressing the suprascapular nerve. This case highlights the importance of considering nerve compression in the differential diagnosis of shoulder pain with muscular weakness in tumoral calcinosis. Surgical decompression of the nerve and excision of the calcified masses resulted in significant pain relief and partial recovery of shoulder function. This report underscores the critical role of imaging in the diagnosis and management of tumoral calcinosis and the potential for favorable outcomes with timely surgical intervention.
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http://dx.doi.org/10.1016/j.radcr.2024.09.111 | DOI Listing |
Equine Vet J
January 2025
Setor de Patologia Veterinária, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Background: In horses, systemic calcinosis is a rare syndrome characterised by muscle lesion associated with the mineralisation of large muscle groups or other organs, in the absence of an alternative cause for the calcification, such as toxic, enzootic or metabolic. Molecular and histopathological aspects of the disease are still poorly elucidated.
Objectives: To describe the epidemiological, pathological and molecular aspects of systemic calcinosis in a convenience sample of six horses submitted to necropsy in the Southern and Midwestern regions of Brazil.
Ren Fail
December 2025
Institute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, Jiangsu, China.
Background: Vascular calcification is highly prevalent and associated with mortality in hemodialysis patients. However, extreme splanchnic arterial calcification in calciphylaxis with poor prognosis raises questions regarding the reliability of previous vascular calcification scoring methods. Therefore, this study aimed to examine the distribution characteristics of abdominal aortic branch calcification and identify a more reliable predictor of mortality in hemodialysis patients.
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January 2025
Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
Background: Cardiovascular disease (CVD) is a leading cause of death in ANCA-associated vasculitis (AAV). Screening and primary cardiovascular prevention may improve outcomes.
Methods: We identified patients in the 2002-2019 Mass General Brigham AAV cohort with thoracic CT scans obtained for other clinical purposes.
J Vet Intern Med
January 2025
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, USA.
Background: Nephrocalcinosis is a common pathological finding in cats with chronic kidney disease and nephrolithiasis. Understanding its pathogenesis may identify future therapeutic targets.
Hypothesis: Nephrocalcinosis is associated with expression of an osteogenic phenotype.
Physiol Meas
January 2025
Department of Vascular Surgery, Jinhua Central Hospital, Jinhua City, Zhejiang Province 321000, People's Republic of China.
To investigate how severe abdominal aortic calcification (SAAC) and estimated pulse wave velocity (ePWV) relate to each other and to all-cause and cardiovascular disease (CVD) mortalities.National Health and Nutrition Examination Survey 2013-2014 data were analyzed. ePWV, computed using age and mean blood pressure, served as an independent variable.
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