Ethnomedicinal breakthroughs in snake bite therapy: From folklore to forefront.

Toxicol Rep

Department of Integrative Biology, School of BioSciences and Technology, VIT, Vellore, India.

Published: December 2024

AI Article Synopsis

  • Snakebite envenomation is a major health issue, particularly in tropical areas like India, causing serious injury and death.
  • The review examines how ethnomedicinal herbs can complement traditional antivenoms, which are often expensive and have availability issues.
  • It also highlights the importance of understanding different snake venoms and the potential of using bioinformatics to enhance antivenom research, merging traditional remedies with modern science for better treatment options.

Article Abstract

Snakebite envenomation is a critical public health issue, especially in tropical regions like India, resulting in significant morbidity and mortality. This review explores the potential of ethnomedicinal herbs as adjunct therapies to conventional antivenoms, addressing challenges such as the high cost, limited availability, and side effects of traditional antivenoms. The study emphasizes regional and species-specific variations in snake venom that complicate antivenom development and highlights the pharmacological potential of certain medicinal plants in mitigating venom effects. These plants offer an affordable, accessible alternative, though their efficacy can vary due to regional venom differences. Additionally, the review discusses the role of bioinformatics in advancing antivenom research, aiming to combine traditional knowledge with modern science to develop effective and accessible snakebite treatments in resource-limited settings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583806PMC
http://dx.doi.org/10.1016/j.toxrep.2024.101795DOI Listing

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