AI Article Synopsis
- A study using Swedish national register data involving over 2.8 million individuals investigated the relationship between divorce and family genetic risk scores (FGRS) for ten psychiatric disorders.
- The findings revealed that individuals who experienced divorce had higher FGRS for all disorders compared to those who remained stably married or never married.
- Additionally, divorced females exhibited higher FGRS than divorced males, and higher FGRS was linked to those who did not remarry or had multiple divorces, highlighting how genetic factors may influence both divorce rates and psychiatric risk.
Article Abstract
We used Swedish national register data ( = 2,828,777) to examine divorce and its associated patterns of family genetic risk scores (FGRS; personalized measures of genetic risk inferred from diagnoses in relatives) across ten psychiatric disorders: major depression, anxiety disorders, obsessive-compulsive disorder, bipolar disorder, schizophrenia, anorexia nervosa, alcohol use disorder, drug use disorder, ADHD, and autism-spectrum disorder. Individuals who divorced had elevated FGRS across all disorders compared to those who were stably married or never married. FGRS for all disorders were higher among divorced females compared to divorced males; among those who did not go on to have a stable second marriage compared to those who had a stable second marriage; and increased as the cumulative number of divorces increased. In summary, genetic predispositions for psychiatric disorders are associated with the propensity to divorce, and with several differences as a function of sex, remarriage, and the cumulative number of divorce transitions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11583951 | PMC |
| http://dx.doi.org/10.1177/21677026231214204 | DOI Listing |
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